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Concomitant benzodiazepine use attenuates ketamine response: implications for large scale study design and clinical development.

作者信息

Frye Mark A, Blier Pierre, Tye Susannah J

机构信息

Department of Psychiatry and Psychology Mayo Clinic Depression Center Mayo Clinic Rochester, MN

出版信息

J Clin Psychopharmacol. 2015 Jun;35(3):334-6. doi: 10.1097/JCP.0000000000000316.

DOI:10.1097/JCP.0000000000000316
PMID:25928701
Abstract
摘要

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Concomitant benzodiazepine use attenuates ketamine response: implications for large scale study design and clinical development.同时使用苯二氮䓬类药物会减弱氯胺酮的反应:对大规模研究设计和临床开发的启示。
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Lamotrigine is not associated with differential clinical outcomes in a real-world sample of patients with unipolar depression receiving ketamine or esketamine.在接受氯胺酮或艾氯胺酮治疗的单相抑郁症患者的真实样本中,拉莫三嗪与不同的临床结果无关。
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Ketamine vs Electroconvulsive Therapy for Treatment-Resistant Depression: A Secondary Analysis of a Randomized Clinical Trial.氯胺酮与电抽搐治疗抵抗性抑郁症的比较:一项随机临床试验的二次分析。
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