Chervenak J L, Chez R A
Department of Obstetrics and Gynecology, New Jersey Medical School, Newark.
J Perinatol. 1989 Dec;9(4):369-71.
We examined the exactness of the timing of the 1-hour glucose sample following a 50-g oral glucose challenge as a critical variable in interpretation of the test. Heparin locks were placed in 45 pregnant patients between 25 and 28 weeks' gestation, and 5 patients between 30 and 33 weeks' gestation. Venous samples were taken at intervals of 50, 60, and 70 minutes from completion of the ingestion of a 50-g oral glucose load. We found all of the nine possible patterns of blood glucose values that can derive from three sequential values. There was no consistent relationship between these 60 +/- 10 minute values. Two of the patients had a 60-minute value greater than 140 mg/dL, but a 50- or 70-minute value that was less than 140 mg/dL. Four of the patients had a 50- or 70-minute value that was greater than 140 mg/dL, but a 60-minute value that was less than 140 mg/mL. The range of results in this study reflects a continuum of values that change rapidly over time and in patterns that are not predictable. We conclude that accurate timing is important to avoid erroneous interpretation of the 1-hour glucose screen.
我们将50克口服葡萄糖耐量试验后1小时血糖样本采集时间的准确性作为该检测结果解读中的一个关键变量进行了研究。对45例孕25至28周的孕妇及5例孕30至33周的孕妇放置了肝素锁。在口服50克葡萄糖负荷结束后的50、60和70分钟时采集静脉血样本。我们发现了由三个连续值得出的所有九种可能的血糖值模式。这些60±10分钟时的值之间没有一致的关系。两名患者60分钟时的值大于140毫克/分升，但50分钟或70分钟时的值小于140毫克/分升。四名患者50分钟或70分钟时的值大于140毫克/分升，但60分钟时的值小于140毫克/毫升。本研究的结果范围反映了一系列随时间快速变化且模式不可预测的值。我们得出结论，准确计时对于避免对1小时血糖筛查结果的错误解读很重要。
