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女性体内的催乳素与性功能障碍

Prolactin and sexual dysfunction in women.

作者信息

Reiss J P, Gupton T W, Faiman C

机构信息

Department of Psychiatry, University of Manitoba, Winnipeg, Canada.

出版信息

J Sex Marital Ther. 1989 Fall;15(3):177-86. doi: 10.1080/00926238908403821.

DOI:10.1080/00926238908403821
PMID:2593155
Abstract

Serum prolactin levels were measured in 48 consecutive sexually dysfunctional women who presented to a sexuality clinic. The prevalence of hyperprolactinemia and mean prolactin level of this group were compared to a control group (blood donor volunteers) of 93 women. One woman in the study group (2.1%) was hyperprolactinemic (serum prolactin greater than 15 micrograms/L). However, the differences in both prevalence of hyperprolactinemia and mean prolactin levels, between groups, were not statistically significant. Neither were differences found in mean prolactin levels among subgroups of women in different diagnostic categories and in those with single vs. multiple diagnoses. Nonetheless, because hyperprolactinemia is readily treatable, we would recommend prolactin determinations in sexually dysfunctional women, particularly in those with associated reproductive irregularity or in whom organic etiology is clinically suspect.

摘要

对48名连续就诊于性健康诊所的性功能障碍女性进行了血清催乳素水平检测。将该组高催乳素血症的患病率和平均催乳素水平与93名女性的对照组(献血志愿者)进行比较。研究组中有1名女性(2.1%)患有高催乳素血症(血清催乳素大于15微克/升)。然而,两组之间高催乳素血症的患病率和平均催乳素水平的差异均无统计学意义。在不同诊断类别的女性亚组以及单诊断与多诊断的女性中,平均催乳素水平也未发现差异。尽管如此,由于高催乳素血症易于治疗,我们建议对性功能障碍女性进行催乳素测定,特别是那些伴有生殖功能异常或临床怀疑有器质性病因的女性。

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