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分化型甲状腺癌的甲状腺切除术完成:何时进行?

Completion thyroidectomy in differentiated thyroid cancer: When to perform?

作者信息

Kısaoğlu Abdullah, Özoğul Bünyami, Akçay Müfide Nuran, Öztürk Gürkan, Atamanalp Sabri Selçuk, Aydınlı Bülent, Kara Salih

机构信息

Department of General Surgery, Atatürk University Faculty of Medicine, Erzurum, Turkey.

出版信息

Ulus Cerrahi Derg. 2014 Mar 1;30(1):18-21. doi: 10.5152/UCD.2014.2486. eCollection 2014.

Abstract

OBJECTIVE

Completion thyroidectomy is recommended in patients who have been diagnosed with differentiated thyroid cancer on histopathological evaluation, if their first operation was a conservative approach. The critical issue is when to do the second operation.

MATERIAL AND METHODS

The medical records of 66 patients who underwent completion thyroidectomy for the treatment of differentiated thyroid cancer in our clinic between 2006-2013 were retrospectively analyzed. All data were compared after patients were divided into two groups according to the interval between the first surgery and completion thyroidectomy.

RESULTS

Fifty-two patients (78.8%) were women and 14 patients (21.2%) were male. Completion thyroidectomy was performed 10-90 days after the initial surgery (group 1) in 26 patients, whereas it was performed later than 90 days in 40 patients (group 2). Temporary hypoparathyroidism occurred in two patients (7.7%) in group 1, and in 3 patients (7.5%) in group 2. Transient recurrent laryngeal nerve palsy was observed in 1 patient (3.9%) in group 1, and in 1 patient (2.5%) in group 2. There were no permanent morbidities in both groups. Residual tumor rate after completion thyroidectomy was 45.5%. There was no statistically significant difference between the two groups in terms of complications after completion thyroidectomy.

CONCLUSION

Although in some studies it is recommended that completion thyroidectomy should be performed either before scar tissue development or after clinical remission of scar tissue, edema and inflammation, we believe that timing of surgery has no effect on morbidity.

摘要

目的

对于经组织病理学评估确诊为分化型甲状腺癌且首次手术采用保守方法的患者,建议行甲状腺全切术。关键问题是何时进行二次手术。

材料与方法

回顾性分析2006年至2013年期间在我院接受甲状腺全切术治疗分化型甲状腺癌的66例患者的病历。根据首次手术与甲状腺全切术之间的间隔时间将患者分为两组后,对所有数据进行比较。

结果

52例患者(78.8%)为女性,14例患者(21.2%)为男性。26例患者(第1组)在初次手术后10 - 90天进行甲状腺全切术,而40例患者(第2组)在90天后进行。第1组有2例患者(7.7%)发生暂时性甲状旁腺功能减退,第2组有3例患者(7.5%)发生。第1组有1例患者(3.9%)出现短暂性喉返神经麻痹,第2组有1例患者(2.5%)出现。两组均无永久性并发症。甲状腺全切术后的残留肿瘤率为45.5%。两组在甲状腺全切术后的并发症方面无统计学显著差异。

结论

尽管在一些研究中建议甲状腺全切术应在瘢痕组织形成之前或瘢痕组织、水肿和炎症临床缓解之后进行,但我们认为手术时机对发病率没有影响。

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