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完成分化型甲状腺癌的甲状腺切除术。

Completion thyroidectomy for differentiated thyroid carcinoma.

作者信息

Eroğlu A, Berberoğlu U, Buruk F, Yildirim E

机构信息

Department of Surgery, Ankara Oncology Hospital, Demetevler, Turkey.

出版信息

J Surg Oncol. 1995 Aug;59(4):261-6; discussion 266-7. doi: 10.1002/jso.2930590413.

Abstract

Completion thyroidectomy is defined as the surgical removal of the remnant thyroid tissue following procedures less than total or near-total thyroidectomy. The extent of surgical management for differentiated thyroid carcinoma (DTC) is controversial. Although some authors advocate subtotal thyroidectomy with lower complication rates, total or near-total thyroidectomy and completion thyroidectomy have been defended by others because of the improved survival and lower morbidity that is comparable with subtotal thyroidectomy. In this study, the incidence of residual tumor and surgical complication rates in patients who underwent completion thyroidectomy were investigated. The medical records of 165 patients undergoing completion thyroidectomy for DTC were reviewed. Seventy-seven (46.6%) of these patients were found to have residual tumor in the remaining thyroid tissue. Anaplastic transformation developed in two of these patients. Permanent bilateral recurrent laryngeal nerve palsy occurred in three patients, and permanent hypoparathyroidism was seen in one patient. We recommend completion thyroidectomy as an efficient and safe method of surgical treatment with a low complication rate for DTC.

摘要

甲状腺次全切除术后甲状腺组织的完全切除定义为在进行了小于全甲状腺切除或近全甲状腺切除手术后,对残余甲状腺组织进行的手术切除。分化型甲状腺癌(DTC)的手术治疗范围存在争议。尽管一些作者主张行甲状腺次全切除术,因其并发症发生率较低,但全甲状腺切除或近全甲状腺切除以及甲状腺次全切除术后的甲状腺组织完全切除术也得到了其他作者的支持,因为它们能提高生存率,且发病率较低,与甲状腺次全切除术相当。在本研究中,我们调查了接受甲状腺组织完全切除术患者的残余肿瘤发生率和手术并发症发生率。回顾了165例因DTC接受甲状腺组织完全切除术患者的病历。其中77例(46.6%)患者在残余甲状腺组织中发现有残余肿瘤。其中2例患者发生了间变。3例患者出现永久性双侧喉返神经麻痹,1例患者出现永久性甲状旁腺功能减退。我们推荐甲状腺组织完全切除术作为一种高效、安全的手术治疗方法,用于治疗DTC,其并发症发生率较低。

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