Liang Yujie, Numan Fahmi Ahmed, Li Kan, Liao Guiqing
Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University Guangzhou, China.
Int J Clin Exp Med. 2015 Feb 15;8(2):2867-73. eCollection 2015.
Tongue is the most important phonatory organ in stomatognathic system. Radical resection of tongue squamous cell carcinoma can cause tongue defect and result in serious oral dysfunction, especially in phonetic function. This study aims to reveal the influence of tongue cancer, tongue defect and tongue reconstructions to phonetic function of tongue cancer patients.
Formant spectrum analysis of Chinese vowels was performed by linear predictive coding (LPC) in tongue squamous cell carcinoma patients (before surgery and 3 months, 9 months and 2 years after surgery) and normal people. Patients with tongue squamous cell carcinoma were divided into reconstruction group and non-reconstruction group. In reconstruction group, patients underwent tongue reconstruction with radial forearm free flap (RFFF) and lateral arm free flap (LAFF), respectively.
45 patients and 40 normal people were included. Differences were statistically significant between patients and normal persons, between patients before surgery and after surgery, between non-reconstruction group and construction group 2 years after operation. No statistical significance was found between patients underwent tongue reconstruction with RFFF or LAFF 2 years after operation.
This study showed that tongue cancer and tongue defect after radical resections affected phonetic function of patients. Tongue reconstruction with free flaps could restore phonetic function to some extent. The efficiency of tongue reconstruction with RFFF and LAFF respectively were similar.
舌是口颌系统中最重要的发声器官。舌鳞状细胞癌根治性切除可导致舌缺损，进而引起严重的口腔功能障碍，尤其是语音功能障碍。本研究旨在揭示舌癌、舌缺损及舌重建对舌癌患者语音功能的影响。
采用线性预测编码（LPC）对舌鳞状细胞癌患者（术前及术后3个月、9个月和2年）及正常人进行汉语元音共振峰频谱分析。舌鳞状细胞癌患者分为重建组和非重建组。重建组患者分别采用游离桡侧前臂皮瓣（RFFF）和游离上臂外侧皮瓣（LAFF）进行舌重建。
纳入45例患者和40名正常人。患者与正常人之间、术前与术后患者之间、术后2年非重建组与重建组之间差异有统计学意义。术后2年采用RFFF或LAFF进行舌重建的患者之间无统计学差异。
本研究表明，舌癌及根治性切除术后的舌缺损影响患者的语音功能。游离皮瓣舌重建可在一定程度上恢复语音功能。RFFF和LAFF舌重建的效果相似。
