He Chao, Ma Xuanpeng
Department of Interventional Radiography, Second Hospital Affiliated to Shaanxi University of Chinese Medicine Xianyang 712000, Shaanxi, China.
Int J Clin Exp Med. 2015 Feb 15;8(2):2958-61. eCollection 2015.
A major cause of female infertility is fallopian tube obstruction and traditional conservative and interventional treatments have been largely unsuccessful, especially in patients with distal tubal obstruction. The objective of the current study was to compare the curative outcome of ozone (treatment group) and conventional interventional treatment (comparison group) through comparing the different effects in the infertility cases caused by fallopian tube obstruction, with the purpose to provide future reference for better treatment regimen for tubal obstruction. 400 infertile cases caused by tubal obstruction admitted in the Second Affiliated Hospital of Shaanxi University of Chinese Medicine from August 2006 to January 2012 were enrolled in this study and received either ozone or conventional interventional treatment. No difference was observed between post-operative proximal tube recanalization rates in the two groups; however, post-operative distal tube recanalization rate and recanalization rate after 6 months were significantly higher in the treatment group. Importantly, the adhesion and conception rates were significantly lower and higher, respectively, in the treatment group compared to the comparison group after six months. Hence, ozone therapy can potentially become a viable treatment modality for far-end tubal obstruction patients.
女性不孕的一个主要原因是输卵管阻塞，传统的保守治疗和介入治疗大多不成功，尤其是对于远端输卵管阻塞的患者。本研究的目的是通过比较臭氧治疗（治疗组）和传统介入治疗（对照组）对输卵管阻塞所致不孕症的不同疗效，比较两者的治疗效果，为输卵管阻塞的更佳治疗方案提供未来参考。选取2006年8月至2012年1月在陕西中医药大学第二附属医院收治的400例输卵管阻塞性不孕症患者，分别接受臭氧治疗或传统介入治疗。两组术后近端输卵管再通率无差异；然而，治疗组术后远端输卵管再通率和6个月后的再通率明显更高。重要的是，6个月后，治疗组的粘连率明显低于对照组，而受孕率明显高于对照组。因此，臭氧治疗可能成为远端输卵管阻塞患者一种可行的治疗方式。
