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脑卒中早期患者耐药性尿潴留的结局

Outcomes of drug-resistant urinary retention in patients in the early stage of stroke.

作者信息

Kim Tae Gyun, Chun Min Ho, Chang Min Cheol, Yang Seoyon

机构信息

Department of Rehabilitation Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

出版信息

Ann Rehabil Med. 2015 Apr;39(2):262-7. doi: 10.5535/arm.2015.39.2.262. Epub 2015 Apr 24.

Abstract

OBJECTIVE

To investigate the prognosis of patients with stroke and urinary retention resistant to alpha blockers and cholinergic agents.

METHODS

Post-void residual urine volume (PVR) was measured in 33 patients with stroke (14 men and 19 women) who were admitted to the department of rehabilitation medicine of our hospital within 30 days after stroke onset. An alpha-blocker and cholinergic agent were administered to patients with PVR >100 mL. If urinary retention had not improved despite the maximum drug doses, the patient was diagnosed with drug-resistant urinary retention. We retrospectively reviewed patient's charts, including PVR at discharge and prognostic factors for PVR.

RESULTS

Ten patients (30.3%) could not void or their PVR was >400 mL at discharge (45.7±15.4 days after onset) after rehabilitation. Twelve patients (36.4%) could void, and their PVR was 100-400 mL. PVR was consistently <100 mL in 11 patients (33.3%). These measurements correlated with the Korean version of the Modified Barthel Index score, Functional Ambulation Category, and the presence of a communication disorder.

CONCLUSION

The results show that 22 patients (66.7%) had incomplete bladder emptying or required catheterization at discharge. Outcomes correlated with functional status, walking ability, and the presence of a communication disorder. Patients with urinary retention and poor general condition require close observation to prevent complications of urinary retention.

摘要

目的

探讨对α受体阻滞剂和胆碱能药物耐药的中风合并尿潴留患者的预后情况。

方法

对我院康复医学科收治的33例中风患者(14例男性,19例女性)在中风发病后30天内测量其排尿后残余尿量(PVR)。对PVR>100 mL的患者给予α受体阻滞剂和胆碱能药物。如果尽管使用了最大药物剂量尿潴留仍未改善,则该患者被诊断为耐药性尿潴留。我们回顾性分析了患者的病历,包括出院时的PVR以及PVR的预后因素。

结果

10例患者(30.3%)在康复后出院时(发病后45.7±15.4天)无法排尿或PVR>400 mL。12例患者(36.4%)能够排尿,其PVR为100 - 400 mL。11例患者(33.3%)的PVR始终<100 mL。这些测量结果与韩国版改良巴氏指数评分、功能步行分类以及是否存在沟通障碍相关。

结论

结果显示,22例患者(66.7%)在出院时膀胱排空不完全或需要导尿。预后与功能状态、步行能力以及是否存在沟通障碍相关。尿潴留且一般状况较差的患者需要密切观察以预防尿潴留的并发症。

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