Tohda S, Nakamura S, Sakamaki H, Onozawa Y
Rinsho Ketsueki. 1989 Oct;30(10):1815-9.
A 73-year-old male was admitted because of slight fever. Systemic lymphadenopathy, polyclonal hypergammaglobulinemia, swelling of pancreas and submaxillary gland and progressing pancytopenia probably by immune mechanism were observed. Histological examination of lymph node showed no destruction of the structure and mild capillary proliferation in the follicle centers. Between follicles, many immunoblasts and mature plasma cells which were polyclonal and mild capillary proliferation were recognized. He was diagnosed as having multicentric Castleman's lymphoma. Administration of prednisolone 10 mg per day improved his symptoms and laboratory data. Then he has been followed up. Referring to the literatures, we discussed the relation between multicentric Castleman's lymphoma and the related diseases.
一名73岁男性因低热入院。观察到全身淋巴结病、多克隆高球蛋白血症、胰腺和颌下腺肿大以及可能由免疫机制导致的全血细胞减少进展。淋巴结组织学检查显示结构未破坏，滤泡中心有轻度毛细血管增生。在滤泡之间，可见许多多克隆免疫母细胞和成熟浆细胞以及轻度毛细血管增生。他被诊断为多中心Castleman病。每天服用10毫克泼尼松龙改善了他的症状和实验室数据。随后对他进行了随访。参考相关文献，我们讨论了多中心Castleman病与相关疾病之间的关系。
