“自我药疗”是检索文献中相关出版物的一个有用术语吗？对相关术语的系统探索。

Is 'self-medication' a useful term to retrieve related publications in the literature? A systematic exploration of related terms.

作者信息

Mansouri Ava, Sarayani Amir, Ashouri Asieh, Sherafatmand Mona, Hadjibabaie Molouk, Gholami Kheirollah

机构信息

Research Center for Rational Use of Drugs, Tehran University of Medical Sciences, Tehran, Iran.

Research Center for Rational Use of Drugs, Tehran University of Medical Sciences, Tehran, Iran; Department of Epidemiology and Biostatistics, School Of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

PLoS One. 2015 May 1;10(5):e0125093. doi: 10.1371/journal.pone.0125093. eCollection 2015.

DOI:10.1371/journal.pone.0125093

PMID:25932634

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4416799/

Abstract

BACKGROUND

Self-Medication (SM), i.e. using medications to treat oneself, is a major concern for health researchers and policy makers. The terms "self medication" or "self-medication" (SM terms) have been used to explain various concepts while several terms have also been employed to define this practice. Hence, retrieving relevant publications would require exhaustive literature screening. So, we assessed the current situation of SM terms in the literature to improve the relevancy of search outcomes.

METHODS

In this Systematic exploration, SM terms were searched in the 6 following databases and publisher's portals till April 2012: Web of Science, Scopus, PubMed, Google scholar, ScienceDirect, and Wiley. A simple search query was used to include only publications with SM terms. We used Relative-Risk (RR) to estimate the probability of SM terms use in related compared to unrelated publications. Sensitivity and specificity of SM terms as keywords in search query were also calculated. Relevant terms to SM practice were extracted and their Likelihood Ratio positive and negative (LR+/-) were calculated to assess their effect on the probability of search outcomes relevancy in addition to previous search queries. We also evaluated the content of unrelated publications. All mentioned steps were performed in title (TI) and title or abstract (TIAB) of publications.

RESULTS

1999 related and 1917 unrelated publications were found. SM terms RR was 4.5 in TI and 2.1 in TIAB. SM terms sensitivity and specificity respectively were 55.4% and 87.7% in TI and 84.0% and 59.5% in TIAB. "OTC" and "Over-The-Counter Medication", with LR+ 16.78 and 16.30 respectively, provided the most conclusive increase in the probability of the relevancy of publications. The most common unrelated SM themes were self-medication hypothesis, drug abuse and Zoopharmacognosy.

CONCLUSIONS

Due to relatively low specificity or sensitivity of SM terms, relevant terms should be employed in search queries and clear definitions of SM applications should be applied to improve the relevancy of publications.

摘要

背景

自我药疗（Self-Medication，SM），即自行用药治疗自身疾病，是健康研究人员和政策制定者主要关注的问题。“自我药疗”或“自我药疗”（SM术语）这些词被用来解释各种概念，同时也有几个术语被用来定义这种行为。因此，检索相关出版物需要详尽的文献筛选。所以，我们评估了文献中SM术语的现状，以提高搜索结果的相关性。

方法

在本次系统探索中，截至2012年4月，在以下6个数据库和出版商门户网站中搜索SM术语：科学引文索引（Web of Science）、Scopus、医学期刊数据库（PubMed）、谷歌学术（Google scholar）、爱思唯尔全文数据库（ScienceDirect）和威利在线图书馆（Wiley）。使用简单的搜索查询，只纳入包含SM术语的出版物。我们使用相对风险（RR）来估计相关出版物与不相关出版物中使用SM术语的概率。还计算了SM术语作为搜索查询关键词的敏感性和特异性。提取与SM行为相关的术语，并计算其阳性似然比和阴性似然比（LR+/-），以评估它们除了先前的搜索查询外对搜索结果相关性概率的影响。我们还评估了不相关出版物的内容。所有提及的步骤均在出版物的标题（TI）和标题或摘要（TIAB）中进行。

结果

共找到1999篇相关出版物和1917篇不相关出版物。SM术语在TI中的RR为4.5，在TIAB中的RR为2.1。SM术语在TI中的敏感性和特异性分别为55.4%和87.7%，在TIAB中的敏感性和特异性分别为84.0%和59.5%。“非处方药”（OTC）和“非处方药物”，其LR+分别为16.78和16.30，对出版物相关性概率的增加提供了最确凿的证据。最常见的不相关SM主题是自我药疗假说、药物滥用和动物自我药疗行为。