Simsek Gokce, Karacayli Ceren, Ozel Aysenur, Arslan Bengi, Muluk Nuray Bayar, Kilic Rahmi
*ENT Department, Faculty of Medicine, Kirikkale University, Kirikkale †Clinic of Social Pediatrics, Dr. Sami Ulus Maternity and Children's Training and Research Hospital, Ministry of Health, Ankara ‡Faculty of Medicine, Kirikkale University, Kirikkale, Turkey.
J Craniofac Surg. 2015 May;26(3):e213-6. doi: 10.1097/SCS.0000000000001437.
Adenotonsillar hypertrophy (ATH) is the most common cause of obstructive sleep apnea in children. This study aimed to evaluate the blood parameters of children with ATH who underwent surgery.
The study included a review of the medical records of 130 children who underwent adenoidectomy or adenotonsillectomy with a diagnosis of adenoid hypertrophy and/or chronic tonsillitis. Patients were classified into 3 groups: group 1 (n=69) underwent adenoidectomy, group 2 (n=61) underwent adenotonsillectomy, and group 3 consisted of 82 healthy children. White blood cell count, platelet count, hemoglobin levels, mean platelet volume, and platelet distribution width values were the primary outcome measures.
Mean platelet volume, platelet distribution width and hemoglobin values decreased in the groups that underwent surgery. Whereas the decrease in group 1 was insignificant, it was significant in group 2. White blood cell count values increased in both group 1 (adenoidectomy) and group 2 (adenotonsillectomy), but the increase in group 2 was significant. No significant difference in platelet count was detected before versus after the operation.
Upper airway obstruction caused by ATH remarkably changes the blood parameters related to chronic hypoxia. Significant improvement can be achieved after adenotonsillectomy rather than adenoidectomy alone.
腺样体扁桃体肥大(ATH)是儿童阻塞性睡眠呼吸暂停最常见的原因。本研究旨在评估接受手术的ATH患儿的血液参数。
该研究回顾了130例诊断为腺样体肥大和/或慢性扁桃体炎并接受腺样体切除术或腺样体扁桃体切除术的患儿的病历。患者分为3组:第1组(n = 69)接受腺样体切除术,第2组(n = 61)接受腺样体扁桃体切除术,第3组由82名健康儿童组成。白细胞计数、血小板计数、血红蛋白水平、平均血小板体积和血小板分布宽度值为主要观察指标。
接受手术的组中平均血小板体积、血小板分布宽度和血红蛋白值下降。第1组下降不显著,而第2组下降显著。第1组(腺样体切除术)和第2组(腺样体扁桃体切除术)的白细胞计数均升高,但第2组升高显著。手术前后血小板计数未检测到显著差异。
ATH引起的上气道阻塞显著改变了与慢性缺氧相关的血液参数。腺样体扁桃体切除术后而非单纯腺样体切除术后可实现显著改善。