Nakagawa Mikiko
Nihon Rinsho. 2015 Apr;73(4):601-5.
Recently, clinical findings showed sex differences in the manifestation of the cardiovascular diseases. There are gender differences in cardiac electrophysiologic properties and the incidence of various types of arrhythmias. Long QT syndrome is more common in women than in men, whereas the incidence of Brugada syndrome and J-wave syndrome are male predominant. The gender differences in QT interval are not observed before puberty but become obvious after puberty. ST-levels markedly increase after puberty in men but not in women, which suggested that the sex hormones have an important role for the ECG parameters and arrhythmias. In addition, gender differences were reported in age-related changes in echocardiographic parameters such as left ventricular diastolic function.