Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Barwon Health, Geelong, Victoria, Australia.
Can J Cardiol. 2015 Jun;31(6):819.e1-2. doi: 10.1016/j.cjca.2015.01.025. Epub 2015 Jan 29.
Epsilon waves are a major criterion for the diagnosis of arrhythmogenic right ventricular cardiomyopathy (ARVC) but are an insensitive sign. Recently, exercise testing has been shown to uncover epsilon waves in asymptomatic patients carrying mutations in the PKP2 gene. We describe a case of an asymptomatic carrier of a mutation in the DSP gene who had a normal baseline electrocardiogram and an exercise-induced epsilon wave. This finding suggests that exercise testing may be valuable for the diagnosis of ARVC and that exercise-induced epsilon waves may be found in various genetic subtypes of this disease.
ε 波是心律失常性右室心肌病 (ARVC) 的主要诊断标准，但敏感性不高。最近，运动试验已被证明可以在携带 PKP2 基因突变的无症状患者中发现 ε 波。我们描述了一例携带 DSP 基因突变的无症状携带者，其基线心电图正常，但运动后出现 ε 波。这一发现表明，运动试验可能对 ARVC 的诊断有价值，并且运动诱导的 ε 波可能出现在该病的各种遗传亚型中。
