Esfehani Maryam Hassan, Mahmoodzadeh Habibollah, Omranipour Ramesh
Department of Surgery, Iranian National Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.
Department of Surgery, Iranian National Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.
J Egypt Natl Canc Inst. 2015 Sep;27(3):171-2. doi: 10.1016/j.jnci.2015.04.001. Epub 2015 Apr 30.
Metastatic tumors involving the small bowel are much more common than primary neoplasms. The most common metastases to the small intestine are those arising from other intra-abdominal organs. Metastases from extra-abdominal tumors are rare but may be found in patients with adenocarcinoma of the breast and carcinoma of the lung. Cutaneous melanoma is the most common extra-abdominal source involving the small intestine, with involvement of the small intestine noted in more than half of the patients dying from malignant melanoma [1]. While intestinal metastasis from sarcoma has been described, this is an extremely rare occurrence especially from a rare malignant sarcoma of cardiac origin. The dismal prognosis of cardiac sarcomas results from extensive local invasion at presentation or distant metastasis. Metastasis to the small bowel may cause obstruction, bleeding, or intussusception in which the diagnosis may be delayed because of rarity of the condition and mild and vague abdominal symptoms at early presentation. In this report, a 35 year old woman a known case of cardiac fibrosarcoma was admitted to the emergency ward with abdominal pain and distention, bloody diarrhea, and recurrent nausea and vomiting. Jejuno-jejunal invagination was diagnosed at laparotomy along with tumoral involvement of the left ovary. Histopathological study showed that there was a fibrosarcoma compatible with the earlier diagnosis of primary cardiac tumor. We have described some aspects of diagnosis and treatment of this rare cause of intestinal intussusception.
累及小肠的转移性肿瘤比原发性肿瘤更为常见。小肠最常见的转移瘤是来自其他腹腔内器官的肿瘤。来自腹腔外肿瘤的转移很少见,但在乳腺癌和肺癌患者中可能会出现。皮肤黑色素瘤是累及小肠的最常见腹腔外来源,死于恶性黑色素瘤的患者中,超过一半有小肠受累[1]。虽然已经描述了肉瘤的肠道转移,但这种情况极为罕见,尤其是源自心脏的罕见恶性肉瘤。心脏肉瘤的预后不佳是由于其在发病时就有广泛的局部侵犯或远处转移。小肠转移可能导致梗阻、出血或肠套叠,由于这种情况罕见且早期表现为轻微和模糊的腹部症状,诊断可能会延迟。在本报告中,一名35岁已知患有心脏纤维肉瘤的女性因腹痛、腹胀、血性腹泻以及反复恶心和呕吐被收入急诊病房。剖腹探查诊断为空肠-空肠套叠,同时左卵巢有肿瘤累及。组织病理学研究表明存在一种纤维肉瘤,与原发性心脏肿瘤的早期诊断相符。我们描述了这种罕见的肠套叠病因的一些诊断和治疗方面。