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胰十二指肠切除术——预防并发症

Pancreatoduodenectomy - preventing complications.

作者信息

Penumadu Prasanth, Barreto Savio G, Goel Mahesh, Shrikhande Shailesh V

机构信息

Department of Gastrointestinal Surgical Oncology, Tata Memorial Center, Mumbai, India.

Department of Gastrointestinal Surgical Oncology, Tata Memorial Center, Mumbai, India ; GI Surgery, GI Oncology & Bariatric Surgery, Medanta Institute of Hepatobiliary & Digestive Sciences, Medanta, The Medicity, Gurgaon, India.

出版信息

Indian J Surg Oncol. 2015 Mar;6(1):6-15. doi: 10.1007/s13193-013-0286-z. Epub 2014 Jan 19.

DOI:10.1007/s13193-013-0286-z
PMID:25937757
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4412861/
Abstract

Increased awareness of periampullary & pancreatic head cancers, and the accompanying improved outcomes following pancreatoduodenectomy (PD), has possibly led to an increase in patients seeking treatment for the same. While there has definitely been a reduction in morbidity rates following PD in the last few decades, this decline has not mirrored the drastic fall in mortality. Amongst the foremost in the factors responsible for this reduction in mortality is the standardization of surgical technique and development of dedicated teams to manage all aspects of this demanding procedure. This review intends to provide the reader with an overview of major complications following this major surgery and measures to prevent them based on the authors' experience.

摘要

对壶腹周围癌和胰头癌的认识提高,以及随之而来的胰十二指肠切除术(PD)后预后改善,可能导致寻求相同治疗的患者增加。虽然在过去几十年中,PD后的发病率肯定有所下降,但这种下降并未反映出死亡率的急剧下降。导致死亡率下降的首要因素包括手术技术的标准化以及组建专门团队来管理这一复杂手术的各个方面。本综述旨在根据作者的经验,为读者提供该大型手术后主要并发症的概述以及预防措施。

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本文引用的文献

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Pylorus resection in partial pancreaticoduodenectomy: impact on delayed gastric emptying.部分胰十二指肠切除术行幽门切除术:对胃排空延迟的影响。
Am J Surg. 2013 Sep;206(3):296-9. doi: 10.1016/j.amjsurg.2012.10.042. Epub 2013 Jun 24.
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Stents for the prevention of pancreatic fistula following pancreaticoduodenectomy.用于预防胰十二指肠切除术后胰瘘的支架
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External stent versus no stent for pancreaticojejunostomy: a meta-analysis of randomized controlled trials.外支架与无支架胰肠吻合术比较:一项随机对照试验的荟萃分析。
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Does fibrin glue sealant decrease the rate of anastomotic leak after a pancreaticoduodenectomy? Results of a prospective randomized trial.纤维蛋白胶密封剂是否能降低胰十二指肠切除术后吻合口漏的发生率?一项前瞻性随机试验的结果。
HPB (Oxford). 2013 Aug;15(8):561-6. doi: 10.1111/hpb.12018. Epub 2012 Dec 27.
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Internal pancreatic duct stent does not decrease pancreatic fistula rate after pancreatic resection: a meta-analysis.胰腺内导管支架并不能降低胰腺切除术后胰瘘的发生率:一项荟萃分析。
Am J Surg. 2013 Jun;205(6):718-25. doi: 10.1016/j.amjsurg.2012.07.039. Epub 2013 Feb 20.
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Evolution of pancreatoduodenectomy in a tertiary cancer center in India: improved results from service reconfiguration.印度一家三级癌症中心的胰十二指肠切除术演变:服务重组带来的更好结果。
Pancreatology. 2013 Jan-Feb;13(1):63-71. doi: 10.1016/j.pan.2012.11.302. Epub 2012 Nov 10.
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Clinical risk factors of delayed gastric emptying in patients after pancreaticoduodenectomy: a systematic review and meta-analysis.胰十二指肠切除术后患者胃排空延迟的临床危险因素:系统评价和荟萃分析。
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