Bon Isabella, Musumeci Giuseppina, Pavoni Michele, Miserocchi Anna, Lo Presti Alessandra, Morini Silvia, Caio Giacomo, Della Vittoria Agnese, Gibellini Davide, Re Maria Carla
Microbiology Section of the Department of Experimental, Diagnostic and Specialty Medicine, School of Medicine, University of Bologna, Italy.
Infectious Diseases Operative Unit, S. Maria delle Croci Hospital, Ravenna, Italy.
New Microbiol. 2015 Apr;38(2):289-92. Epub 2015 Apr 29.
We describe the case of a young woman with an acute HIV infection characterized at onset by neurological features. The patient spontaneously controlled her HIV infection and recovered in a short period of time. The patient's clinical and virological history showed a peculiar evolution of HIV infection, with an MDR HIV-1 in CSF and a wild HIV strain in PBMCs. The patient's PBMC showed a rapid shift from a wild type to an MDR strain in few days.
我们描述了一名年轻女性急性HIV感染的病例，其起病时具有神经系统特征。该患者自发控制了HIV感染，并在短时间内康复。患者的临床和病毒学病史显示出HIV感染的特殊演变过程，脑脊液中有耐多药HIV-1，外周血单核细胞中有野生HIV毒株。患者的外周血单核细胞在几天内迅速从野生型转变为耐多药毒株。
