对胆固醇水平较低的心肌梗死患者残余风险的管理。
Managing residual risk after myocardial infarction among individuals with low cholesterol levels.
作者信息
Colantonio Lisandro D, Bittner Vera
机构信息
Department of Epidemiology, University of Alabama at Birmingham, 1530 3rd Avenue South, RPHB 217C, Birmingham, AL 35294, USA.
Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, 701 19th Street South, LHRB 310, Birmingham, AL 35294, USA.
出版信息
Cardiol Clin. 2015 May;33(2):299-308. doi: 10.1016/j.ccl.2015.01.004.
About one-half of individuals with an acute myocardial infarction have a low-density lipoprotein cholesterol level of less than 100 mg/dL at the time of occurrence, but remain at risk for recurrent events. This residual risk is likely mediated by multiple factors, including burden of atherosclerosis, residual dyslipidemia, nonlipid risk factors, and suboptimal implementation of lifestyle therapy and evidence-based pharmacologic therapy. This article reviews management options for this high-risk population.
约一半急性心肌梗死患者在发病时低密度脂蛋白胆固醇水平低于100mg/dL，但仍有复发事件的风险。这种残余风险可能由多种因素介导，包括动脉粥样硬化负担、残余血脂异常、非脂质风险因素以及生活方式治疗和循证药物治疗的实施欠佳。本文综述了针对这一高危人群的管理方案。
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