Campbell Bruce C V, Mitchell Peter J, Dowling Richard J, Yan Bernard, Donnan Geoffrey A, Davis Stephen M
Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia.
Department of Radiology, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia.
Heart Lung Circ. 2015 Aug;24(8):733-5. doi: 10.1016/j.hlc.2015.04.001. Epub 2015 Apr 21.
Cardiologists often remark that the field of ischaemic stroke follows in the footsteps of cardiology, just one to two decades later. In the case of endovascular reperfusion therapies this certainly seems to have been the case but there are now multiple positive randomised trials establishing the benefit of mechanical thrombectomy over and above standard care, which included intravenous alteplase in most cases. We will outline the new evidence, contrast the recent trials with the earlier negative studies and discuss some important differences between acute myocardial infarction and ischaemic stroke and the techniques required to treat them.
心脏病专家常说,缺血性中风领域是在心脏病学之后发展起来的,只是晚了一二十年。就血管内再灌注治疗而言,情况似乎确实如此,但现在有多项阳性随机试验证实了机械取栓术优于标准治疗的益处,在大多数情况下,标准治疗包括静脉注射阿替普酶。我们将概述新证据,将近期试验与早期阴性研究进行对比,并讨论急性心肌梗死和缺血性中风之间的一些重要差异以及治疗它们所需的技术。