Narayan Sujita W, Nishtala Prasad S
School of Pharmacy, University of Otago, Dunedin, New Zealand.
J Eval Clin Pract. 2015 Aug;21(4):633-41. doi: 10.1111/jep.12355. Epub 2015 May 4.
RATIONAL, AIMS AND OBJECTIVES: To examine the prevalence of potentially inappropriate medicines (PIMs) in older New Zealanders at a population level.
De-identified prescription data for all individuals ≥65 years were obtained from the Pharmaceutical Claims Data Mart for 2011. International Classification of Diseases-10-AM (version 6) codes were used to extract diagnostic information from the National Minimum Datasets and PIMs were identified using the updated Beers 2012 criteria.
40.9% of older people were prescribed PIMs with approximately half dispensed ≥2 PIMs in 2011. Exposure was highest in individuals aged 65-74 years (68.9 ± 2.9). The most prevalent PIMs dispensed were diclofenac (6.0%), amitriptyline (4.9%), ibuprofen (4.6%), zopiclone (3.2%) and naproxen (3.0%). 66.3% of individuals were dispensed ≥1 and 80.8% were dispensed ≥2 medicines with a potential for drug-disease/syndrome interaction.
The updated Beers 2012 criteria identified that the use of PIMs at a population level is common in older New Zealanders.
在人群层面调查新西兰老年人中潜在不适当用药（PIMs）的流行情况。
从2011年药品报销数据集市获取所有65岁及以上个体的匿名处方数据。使用国际疾病分类第10版澳大利亚和新西兰修订本（第6版）编码从国家最低数据集提取诊断信息，并使用更新后的2012年Beers标准识别PIMs。
2011年，40.9%的老年人被开具了PIMs，约一半人配到了两种及以上的PIMs。65 - 74岁人群的暴露率最高（68.9 ± 2.9）。最常配到的PIMs是双氯芬酸（6.0%）、阿米替林（4.9%）、布洛芬（4.6%）、佐匹克隆（3.2%）和萘普生（3.0%）。66.3%的人配到了至少一种、80.8%的人配到了至少两种有药物 - 疾病/综合征相互作用可能性的药物。
更新后的2012年Beers标准表明，在新西兰老年人中，人群层面使用PIMs的情况很常见。
