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急性灌注不良综合征主动脉夹层:漏斗技术经皮腔内血管开窗术。

Aortic dissection with acute malperfusion syndrome: Endovascular fenestration via the funnel technique.

机构信息

Clinique Universitaire de Radiologie et d'Imagerie Médicale, Centre Hospitalier Universitaire de Grenoble, Grenoble, France.

Clinique Universitaire de Radiologie et d'Imagerie Médicale, Centre Hospitalier Universitaire de Grenoble, Grenoble, France.

出版信息

J Thorac Cardiovasc Surg. 2015 Jul;150(1):108-15. doi: 10.1016/j.jtcvs.2015.03.056. Epub 2015 Apr 2.

DOI:10.1016/j.jtcvs.2015.03.056
PMID:25940416
Abstract

OBJECTIVE

To analyze the short- and long-term results of an original aortic fenestration method using the funnel technique during aortic dissection complicated by malperfusion syndrome.

METHODS

The funnel technique consists of deployment of an uncovered aortic stent graft placed from the false to the right lumen through an intimal flap aortic fenestration made by balloon angioplasty. Twenty-eight patients presenting with an aortic dissection (type A, n = 19; type B, n = 9) were treated for malperfusion syndrome owing to dynamic compression (16 renal, 17 bowel, and 13 lower limb ischemia) using the aforementioned technique, and had follow-up evaluation at short term (30 days) and long term (mean: 55 ± 40 months). Eight patients had severe ischemia on arrival (6 bowel, 7 renal, 3 lower limb).

RESULTS

Technical success was achieved in 27 of 28 patients (96%), and ischemic symptoms had disappeared in 25 of 28 patients (89%) at short-term follow up. Five patients presented postprocedure complications: 4 minor and 1 major with arterial thrombosis which caused technical failure (3.6%). The 30-day mortality rate was 7% (n = 2), related to bowel ischemia complications. At long-term follow up, 21 patients had a stable thoracic aortic diameter (91%).

CONCLUSIONS

The funnel technique, in cases of malperfusion syndrome after aortic dissection, safely improves short- and long-term clinical outcome, and could represent an interesting alternative in the management of patients. The hemodynamic efficiency of this technique may account for a lower mortality in our series.

摘要

目的

分析使用漏斗技术进行主动脉开窗治疗伴有灌注不良综合征的主动脉夹层的短期和长期结果。

方法

漏斗技术包括通过球囊血管成形术制作的内膜瓣主动脉开窗,将未覆膜的主动脉支架移植物从假腔到右腔。28 例因动态压迫(16 例肾,17 例肠,13 例下肢缺血)而出现主动脉夹层(A型 19 例,B 型 9 例)的患者接受了上述技术治疗,并进行了短期(30 天)和长期(平均:55±40 个月)随访评估。8 例患者在入院时出现严重缺血(6 例肠,7 例肾,3 例下肢)。

结果

28 例患者中 27 例(96%)技术成功,25 例(89%)患者在短期随访中缺血症状消失。5 例患者出现术后并发症:4 例轻微,1 例动脉血栓形成导致技术失败(3.6%)。30 天死亡率为 7%(n=2),与肠缺血并发症有关。长期随访时,21 例患者的胸主动脉直径稳定(91%)。

结论

在主动脉夹层并发灌注不良综合征的情况下,漏斗技术可安全改善短期和长期临床结局,可能是该类患者治疗的一种有趣选择。该技术的血流动力学效率可能是我们系列中死亡率较低的原因。

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