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[穿透性角膜移植术与供体角膜后弹力层剥除自动内皮角膜移植术用于对侧眼:功能结果与患者满意度]

[Perforating keratoplasty versus Descemet stripping automated endothelial keratoplasty in the partner eye: Functional results and patient satisfaction].

作者信息

Gross N J, Böhringer D, Maier P, Reinhard T

机构信息

Klinik für Augenheilkunde, Universitätsklinikum Freiburg, 79106, Freiburg im Breisgau, Deutschland.

出版信息

Ophthalmologe. 2015 Oct;112(10):848-53. doi: 10.1007/s00347-015-0010-1.

Abstract

BACKGROUND

This study compared the postoperative results and patient satisfaction between penetrating keratoplasty (PK) and Descemet stripping automated endothelial keratoplasty (DSAEK) in patients who underwent PK in one eye and DSAEK in the other eye.

METHODS

A total of 15 patients were identified from the corneal database register and the medical charts were analyzed for best corrected visual acuity (BCVA), keratometric astigmatism, endothelial cell density and postoperative complications. Patient satisfaction was evaluated by a standardized interview.

RESULTS

Median follow-up time for PK was 55 months and 18 months for DSAEK (p < 0.01). Median BCVA in PK was 0.8 and 0.5 in DSAEK (p = 0.01) at the end of follow-up. Median keratometric astigmatism was 3.1 diopters after PK and 1.9 diopters after DSAEK (p = 0.2). Median endothelial cell density was 831 cells/mm(2) after PK and 860 cells/mm(2) after DSAEK (p = 0.63). For the interventions 57 % of the patients preferred PK, 36 % preferred DSAEK and 7 % were undecided. Patients assigned the better performing eye to the PK side in 64 % and in 29 % to the DSAEK side and 7 % perceived equal visual performance in both eyes.

CONCLUSION

The results leave doubt about the superiority of DSAEK compared to PK; however, exceptionally good refractive results of the 15 PK eyes analyzed and significantly longer follow-up times after PK could be the reason for the unexpectedly high patient preference for PK.

摘要

背景

本研究比较了在一只眼睛接受穿透性角膜移植术(PK)而另一只眼睛接受Descemet膜剥除自动内皮角膜移植术(DSAEK)的患者的术后结果和患者满意度。

方法

从角膜数据库登记中识别出总共15例患者,并分析病历以获取最佳矫正视力(BCVA)、角膜散光、内皮细胞密度和术后并发症。通过标准化访谈评估患者满意度。

结果

PK的中位随访时间为55个月,DSAEK为18个月(p < 0.01)。随访结束时,PK的中位BCVA为0.8,DSAEK为0.5(p = 0.01)。PK后的中位角膜散光为3.1屈光度,DSAEK后为1.9屈光度(p = 0.2)。PK后的中位内皮细胞密度为831个细胞/mm²,DSAEK后为860个细胞/mm²(p = 0.63)。对于这些干预措施,57%的患者更喜欢PK,36%更喜欢DSAEK,7%未作决定。64%的患者将表现较好的眼睛归为PK侧,29%归为DSAEK侧,7%认为两只眼睛的视力表现相同。

结论

结果使人对DSAEK相对于PK的优越性产生怀疑;然而,所分析的15只PK眼睛异常良好的屈光结果以及PK后明显更长的随访时间可能是患者对PK出乎意料地高度偏好的原因。

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