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挪威青春期前女孩学校常规疫苗接种中HPV疫苗接种率的相关因素:一项基于登记册的对90000名女孩及其父母的研究。

Correlates of HPV vaccine uptake in school-based routine vaccination of preadolescent girls in Norway: A register-based study of 90,000 girls and their parents.

作者信息

Hansen Bo Terning, Campbell Suzanne, Burger Emily, Nygård Mari

机构信息

Department of Research, Cancer Registry of Norway, Oslo, Norway.

Department of Health Management and Health Economics, University of Oslo, Oslo, Norway.

出版信息

Prev Med. 2015 Aug;77:4-10. doi: 10.1016/j.ypmed.2015.04.024. Epub 2015 May 3.

DOI:10.1016/j.ypmed.2015.04.024
PMID:25944266
Abstract

OBJECTIVE

To assess demographic, socioeconomic and behavioural correlates of HPV vaccination of preadolescent girls in a publicly funded, school-based vaccination programme.

METHODS

Data for all Norwegian girls born 1997-1999, eligible for routine school-based HPV vaccination in 2009-2011 (n=90,842), and their registered mother and father, were merged from national registries. Correlates of girl vaccination status were analysed by unadjusted and multivariable logistic regression.

RESULTS

In total, 78.2% of the girls received the first dose of the HPV vaccine, 74.6% received three doses, and 94.8% received the MMR vaccine. Correlates associated with initiation of HPV vaccination included parental age, income and education, maternal occupational status and cervical screening attendance, and girl receipt of the MMR vaccine. Rates of completion of HPV vaccination among initiators were high, and disparities in completion were negligible. Maternal and paternal correlates of daughter HPV vaccination status were similar.

CONCLUSIONS

Routine school-based vaccination generally provides equitable delivery, yet some disparities exist. Information campaigns designed to reach the sub-groups with relatively low vaccine uptake could reduce disparities. In none of the sub-groups investigated did uptake of the HPV vaccine approach that of the MMR vaccine, further demonstrating a general potential for improvement in HPV vaccine uptake.

摘要

目的

在一项由公共资金支持的、基于学校的疫苗接种计划中,评估青春期前女孩HPV疫苗接种的人口统计学、社会经济和行为学相关因素。

方法

将2009 - 2011年有资格接受常规学校HPV疫苗接种的所有挪威1997 - 1999年出生女孩(n = 90,842)及其登记的父母的数据从国家登记处合并。通过未调整和多变量逻辑回归分析女孩疫苗接种状况的相关因素。

结果

总体而言,78.2%的女孩接种了第一剂HPV疫苗,74.6%的女孩接种了三剂,94.8%的女孩接种了MMR疫苗。与开始HPV疫苗接种相关的因素包括父母年龄、收入和教育程度、母亲职业状况和宫颈筛查参与情况,以及女孩接种MMR疫苗的情况。开始接种HPV疫苗者的完成率很高,完成情况的差异可以忽略不计。女儿HPV疫苗接种状况的母亲和父亲相关因素相似。

结论

基于学校的常规疫苗接种通常能实现公平接种,但仍存在一些差异。针对疫苗接种率相对较低的亚组开展的宣传活动可能会减少差异。在所调查的任何亚组中,HPV疫苗的接种率都未达到MMR疫苗的接种率,这进一步表明HPV疫苗接种率总体上还有提升空间。

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