[Antiatherogenic properties of the soy protein isolate 500 E].

Two and 4 hours after a single intake of 50 g of protein isolate soy 500 E in the food, the activity of lysosomal hydrolases in blood platelets, the cholesterol (CS) content in lipoprotein-containing immune complexes, and the accumulation of CS in the subendothelial cells of human aorta intima reduced in introduction into a culture of serum obtained after intake of protein isolate soy. Direct introduction of a isolate 500 E water-alcohol extract into a culture of atherosclerotic plaques of human aorta intima caused decrease of the CS content in the cells and their proliferation. Protein isolate soy, therefore, produces an antiatherogenic effect in a cell culture and causes the antiatherosclerotic properties of serum.