Globerman Dobrochna, Robert Magali
Division of Urogynecology, Department of Obstetrics and Gynecology, 1403 29 St NW, Calgary, AB, T2N 2T9, Canada,
Int Urogynecol J. 2015 Sep;26(9):1373-8. doi: 10.1007/s00192-015-2720-y. Epub 2015 May 6.
This review aimed to examine post-intervention prolapse, incontinence, and overactive bladder outcome measures published in the International Urogynecology Journal over the previous year and to report on the heterogeneity in outcome reporting.
All original article abstracts published in the print version of the International Urogynecology Journal in 2014 were reviewed for possible inclusion. Those reporting on prolapse and/or incontinence and/or overactive bladder outcomes following a urogynecological intervention were analyzed. Articles were reviewed for all reported outcomes. Outcomes were categorized as primary or secondary and objective or subjective.
Of 117 original articles published, 45 were reviewed. Among primary outcomes, 9 different outcomes were reported for prolapse and 11 for incontinence and overactive bladder. For prolapse, 6 different objective and 13 subjective outcomes were reported. For incontinence, 21 objective and 36 subjective outcomes were reported. Three different definitions were used for the outcome of "prolapse cure," 3 for "prolapse recurrence," and 4 for "stress incontinence cure." Several validated and non-validated questionnaires in addition to single unvalidated questions were used to measure subjective outcomes.
This research highlights the diversity in outcome reporting for prolapse, incontinence, and overactive bladder after an intervention in the last year of publications alone. This can lead to serious challenges in the generation of higher order evidence, such as systematic reviews and meta-analyses. As a subspecialty, we need to aim for more cohesive reporting so as to allow for robust comparison and evidence dissemination.
本综述旨在研究上一年发表在《国际尿控协会杂志》上的干预后脱垂、尿失禁和膀胱过度活动症的结局指标，并报告结局报告中的异质性。
对2014年《国际尿控协会杂志》印刷版上发表的所有原创文章摘要进行审查，以确定是否可能纳入。分析那些报告了泌尿妇科干预后脱垂和/或尿失禁和/或膀胱过度活动症结局的文章。对所有报告的结局进行审查。结局分为主要或次要结局以及客观或主观结局。
在发表的117篇原创文章中，45篇被审查。在主要结局中，报告了9种不同的脱垂结局、11种尿失禁和膀胱过度活动症结局。对于脱垂，报告了6种不同的客观结局和13种主观结局。对于尿失禁，报告了21种客观结局和36种主观结局。“脱垂治愈”结局使用了3种不同的定义，“脱垂复发”使用了3种，“压力性尿失禁治愈”使用了4种。除了单个未经验证的问题外，还使用了几种经过验证和未经验证的问卷来测量主观结局。
本研究仅突出了在去年发表的文献中，干预后脱垂、尿失禁和膀胱过度活动症结局报告的多样性。这可能会给生成更高层次的证据（如系统评价和荟萃分析）带来严重挑战。作为一个亚专业，我们需要致力于更具一致性的报告，以便进行有力的比较和证据传播。
