Ni Xiaoting, Qin Siyuan, Lou Zhilong, Ning Hongrui, Sun Xiaolin
College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, Gansu 730070, China ; State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu 730046, China.
State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu 730046, China ; College of Animal Science and Technology, Jilin Agriculture University, Changchun, Jilin 130118, China.
Biomed Res Int. 2015;2015:460473. doi: 10.1155/2015/460473. Epub 2015 Apr 5.
Chlamydia spp. are obligate intracellular bacteria distributed all over the world, known to cause various forms of diseases in animals and humans. In the present study, a serological survey was conducted to detect the seroprevalence and risk factors associated with rabbit chlamydiosis in northeast China, including Liaoning province, Jilin province, Heilongjiang province, and Inner Mongolia Autonomous Region. Antibodies to Chlamydia were determined by indirect hemagglutination assay (IHA). The overall seroprevalence was estimated at 17.88% in total of 800 blood samples. The Chlamydia seroprevalence varied in domestic rabbits from different factors, and genders of domestic rabbits were considered as major risk factors associated with Chlamydia infection. Our study revealed a widespread and high prevalence of Chlamydia infection in domestic rabbits in northeast China, with higher exposure risk in female domestic rabbits. These findings suggested the potential importance of domestic rabbits in the transmission of zoonotic Chlamydia infection, and thus Chlamydia should be taken into consideration in diagnosing rabbit diseases. To our knowledge, there is no report of Chlamydia infection in domestic rabbits in China and the results extend the host range for Chlamydia, which has important implications for public health and the local economy.
衣原体属是专性细胞内细菌，分布于世界各地，已知可在动物和人类中引发各种疾病。在本研究中，开展了一项血清学调查，以检测中国东北地区（包括辽宁省、吉林省、黑龙江省和内蒙古自治区）兔衣原体病的血清流行率及相关风险因素。通过间接血凝试验（IHA）检测衣原体抗体。在总共800份血样中，总体血清流行率估计为17.88%。家兔衣原体血清流行率因不同因素而有所差异，家兔的性别被视为与衣原体感染相关的主要风险因素。我们的研究表明，中国东北地区家兔衣原体感染广泛且流行率高，雌性家兔的暴露风险更高。这些发现提示家兔在人畜共患衣原体感染传播中的潜在重要性，因此在诊断兔病时应考虑衣原体。据我们所知，中国尚无家兔衣原体感染的报告，本研究结果扩展了衣原体的宿主范围，对公共卫生和当地经济具有重要意义。
