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Are we correctly diagnosing adrenal insufficiency or are we just spitting into the wind?我们对肾上腺功能不全的诊断是否正确，还是只是在白费力气？
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Salivary biomarkers may measure stress responses in critically ill children.唾液生物标志物可能用于测量危重症儿童的应激反应。
SAGE Open Med. 2018 Sep 25;6:2050312118802452. doi: 10.1177/2050312118802452. eCollection 2018.

本文引用的文献

1
Measurement of salivary cortisol level for the diagnosis of critical illness-related corticosteroid insufficiency in children.测量唾液皮质醇水平用于诊断儿童危重症相关皮质类固醇激素缺乏症。
Pediatr Crit Care Med. 2015 May;16(4):e101-6. doi: 10.1097/PCC.0000000000000361.
2
Incidence of adrenal insufficiency and impact of corticosteroid supplementation in critically ill children with systemic inflammatory syndrome and vasopressor-dependent shock.全身炎症综合征伴血管加压素依赖性休克危重症患儿肾上腺皮质功能不全的发生率及皮质类固醇补充治疗的影响。
Crit Care Med. 2011 May;39(5):1145-50. doi: 10.1097/CCM.0b013e31820eb4e4.
3
Real-time free cortisol quantification among critically ill children.危重症儿童实时游离皮质醇定量检测。
Pediatr Crit Care Med. 2011 Sep;12(5):525-31. doi: 10.1097/PCC.0b013e3181fe4474.
4
Salivary and free serum cortisol evaluation.唾液和游离血清皮质醇评估。
Mil Med. 2010 May;175(5):340-6. doi: 10.7205/milmed-d-09-00166.
5
A prospective multicenter study of adrenal function in critically ill children.一项关于危重症患儿肾上腺功能的前瞻性多中心研究。
Am J Respir Crit Care Med. 2010 Jul 15;182(2):246-51. doi: 10.1164/rccm.200911-1738OC. Epub 2010 Mar 18.
6
Salivary cortisol as an alternative for serum cortisol in the low-dose adrenocorticotropic hormone stimulation test?唾液皮质醇作为小剂量促肾上腺皮质激素刺激试验中血清皮质醇的替代指标？
J Endocrinol Invest. 2010 Feb;33(2):92-5. doi: 10.1007/BF03346560. Epub 2009 Jul 28.
7
Serum free cortisol index, free cortisol, and total cortisol in critically ill children.危重症患儿的血清游离皮质醇指数、游离皮质醇和总皮质醇
Intensive Care Med. 2009 Jul;35(7):1281-5. doi: 10.1007/s00134-009-1480-x. Epub 2009 Apr 8.
8
Endocrine issues in the pediatric intensive care unit.儿科重症监护病房中的内分泌问题。
Pediatr Clin North Am. 2008 Jun;55(3):805-33, xiii. doi: 10.1016/j.pcl.2008.03.001.
9
Identification of adrenal insufficiency in pediatric critical illness.小儿危重症中肾上腺皮质功能不全的识别
Pediatr Crit Care Med. 2007 May;8(3):276-8. doi: 10.1097/01.PCC.0000262796.38637.15.
10
Measurement of serum free cortisol shows discordant responsivity to stress and dynamic evaluation.血清游离皮质醇的测量显示对应激和动态评估的反应不一致。
J Clin Endocrinol Metab. 2007 May;92(5):1729-35. doi: 10.1210/jc.2006-2361. Epub 2007 Mar 6.

Are we correctly diagnosing adrenal insufficiency or are we just spitting into the wind?

作者信息

Nelson Lara P, Markovitz Barry P

机构信息

Departments of Pediatrics and Anesthesiology Critical Care Medicine, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA.

出版信息

Pediatr Crit Care Med. 2015 May;16(4):385-6. doi: 10.1097/PCC.0000000000000388.

DOI:10.1097/PCC.0000000000000388
PMID:25946267
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4425213/
Abstract
摘要