Duann Y H, Wu C M, Shen C L
Department of Anatomy, College of Medicine, National Cheng Kung University, Tainan, Taiwan, Republic of China.
Proc Natl Sci Counc Repub China B. 1989 Jul;13(3):218-29.
Immunohistochemical techniques were employed to study the distribution of serotonin (5-HT) immunoreactive neurons in the brainstem of the hamster, guinea pig, rabbit and rat. 5-HT neurons were principally found to be concentrated in the midline raphe nuclei, particularly, the raphe pallidus, raphe obscurus, raphe magnus, raphe median, raphe pontis and raphe dorsalis nuclei. Characteristically, these cell bodies are displayed in bands or wing-like patterns which extend laterally from the raphe into reticular formations. The formations often appear to blend with the catecholamine system. They are particularly evident in the brainstems of the rabbit and hamster which contain wider and more lateral extensions of the serotonergic (5-HT) neurons than those observed in the brainstems of the rat and guinea pig. The widespread distribution of 5-HT immunoreacted cell bodies in the brainstem shows that there are significant prospects of 5-HT in neuronal activities.
采用免疫组织化学技术研究了仓鼠、豚鼠、兔和大鼠脑干中5-羟色胺（5-HT）免疫反应性神经元的分布。主要发现5-HT神经元集中在中缝核，特别是中缝苍白核、中缝隐核、中缝大核、中缝正中核、中缝脑桥核和中缝背核。其特点是，这些细胞体呈带状或翼状分布，从中缝向外侧延伸至网状结构。这些结构常与儿茶酚胺系统融合。它们在兔和仓鼠的脑干中尤为明显，其脑干中5-羟色胺能（5-HT）神经元的分布比大鼠和豚鼠的脑干更广泛、更靠外侧。5-HT免疫反应性细胞体在脑干中的广泛分布表明，5-HT在神经元活动中具有重要的作用前景。
