Choudhury Monisha, Rautela Archna, Nain Manupriya
Department of Pathology, Lady Hardinge Medical College, New Delhi, India.
J Cytol. 2015 Jan-Mar;32(1):42-5. doi: 10.4103/0970-9371.155235.
Myxopapillary ependymoma (MPE) is a rare and distinctive tumor which occurs in the sacrococcygeal area of young adults and children, often intradural in location. Histopathologic features have been well-described in the literature whereas cytological findings have been sporadically reported by various authors mainly as case reports. We report the features of a primary sacrococcygeal MPE on aspirate cytology in a 45-year-old female. Cytology smears displayed a papillary pattern with the presence of fibrovascular cores, rimmed by cuboidal to columnar cells sending fibrillary cytoplasmic processes forming pseudorosettes along with the presence of hyaline globules, and myxoid material. Intranuclear inclusions, nuclear grooves, cytologic atypia or mitotic activity was not evident, in this case. MPEs need to be differentiated from the other tumors occurring in this location which may also show myxoid material and papillary fronds. Hence, the recognition of the characteristic cytologic features plays an important role in establishing a preoperative diagnosis.
黏液乳头型室管膜瘤（MPE）是一种罕见且独特的肿瘤，发生于年轻成年人和儿童的骶尾部区域，通常位于硬膜内。组织病理学特征在文献中已有详尽描述，而细胞学表现主要由不同作者零星报道，多为病例报告。我们报告了一名45岁女性原发性骶尾部MPE的穿刺细胞学特征。细胞学涂片显示为乳头样结构，有纤维血管轴心，被立方状至柱状细胞围绕，这些细胞发出纤维状胞质突起，形成假菊形团，同时伴有透明小球和黏液样物质。在本例中，未见核内包涵体、核沟、细胞异型性或有丝分裂活性。MPE需要与发生于该部位的其他肿瘤相鉴别，这些肿瘤也可能表现出黏液样物质和乳头样结构。因此，识别特征性的细胞学特征对术前诊断起着重要作用。
