Saify Fatema Y, Gosavi Suchitra R
Department of Oral Pathology, Government Dental College, Raipur, Chhattisgarh, India.
Department of Oral Pathology, Government Dental College, Nagpur, Maharashtra, India.
J Oral Maxillofac Pathol. 2014 Sep-Dec;18(3):411-4. doi: 10.4103/0973-029X.151333.
Gorham's disease is a rare disorder of uncertain etiology characterized by spontaneous and progressive osteolysis of one or more skeletal bones. Till date, less than 200 cases have been reported in the international literature with about 51 cases involving the maxillofacial site. The radiographic findings associated with Gorham's disease are particularly dramatic, as in some cases a complete resorption of the involved bone can occur, leading to the definition of phantom bone or disappearing bone disease. The purpose of this review is to make our community aware of this rare entity and to discuss the etiopathology, clinical presentation, radiographic findings, histopathology, differential diagnoses and treatment modalities for patients with vanishing bone disease.
戈勒姆病是一种病因不明的罕见疾病，其特征为一个或多个骨骼出现自发性进行性骨质溶解。迄今为止，国际文献报道的病例不足200例，其中约51例累及颌面部位。与戈勒姆病相关的影像学表现尤为显著，在某些病例中，受累骨骼可完全吸收，从而导致“幻影骨”或“消失骨病”的定义。本综述的目的是让我们的同行了解这种罕见疾病，并讨论消失骨病患者的病因病理、临床表现、影像学表现、组织病理学、鉴别诊断及治疗方式。
