Sinha Rupam, Sarkar Soumyabrata, Khaitan Tanya, Ramani Deepsikha
Dept. of Oral Medicine & Radiology, Haldia Institute of Dental Sciences and Research, Haldia, West Bengal, India.
Dept. of Dentistry, Murshidabad Medical College and Hospital, Berhampore, West Bengal, India.
Iran J Pathol. 2017 Summer;12(3):301-306. Epub 2017 Jul 1.
Gorham's disease is a rare and atypical disorder epitomized by progressive osteolysis of bone with eventual total disappearance of bone. The etiology is poorly understood with variable clinical presentation. Most times it is initially misdiagnosed as temporomandibular joint dysfunction, periodontal disease or odontogenic tumors clinically and radiographically in routine dental practice. Radiographic examination, such as Cone Beam Computerized Tomography (CBCT) play a vital role in diagnosing such disorder resulting in disappearance of the involved bone entirely, which is a definitive distinguishing feature of this condition. Regarding the rarity of the condition, the current study presents a case of Gorham's disease with distinctive clinical, radiological, and histological, features involving maxilla and mandible.
戈勒姆病是一种罕见的非典型疾病,其特征是骨骼进行性骨质溶解,最终骨骼完全消失。病因尚不清楚,临床表现多样。在常规牙科实践中,大多数情况下,临床上和影像学上最初会被误诊为颞下颌关节功能紊乱、牙周病或牙源性肿瘤。影像学检查,如锥形束计算机断层扫描(CBCT),在诊断这种疾病中起着至关重要的作用,其结果是受累骨骼完全消失,这是这种疾病的一个明确特征。鉴于这种疾病的罕见性,本研究报告了一例累及上颌骨和下颌骨的具有独特临床、放射学和组织学特征的戈勒姆病病例。