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自然双胎妊娠对肾移植功能及血流动力学的影响。

The effect of spontaneous twin pregnancy on renal transplant function and haemodynamics.

作者信息

Cheung Chee Kay, Bhandari Sunil

机构信息

Department of Renal Medicine , Hull and East Yorkshire Hospitals NHS Trust and Hull York Medical School , East Yorkshire, HU3 2JZ , UK.

出版信息

NDT Plus. 2010 Feb;3(1):48-50. doi: 10.1093/ndtplus/sfp137. Epub 2009 Sep 23.

DOI:10.1093/ndtplus/sfp137
PMID:25949404
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4421557/
Abstract

Spontaneous twin pregnancy is rare in renal transplant recipients, and confers a significant risk, in terms of both transplant dysfunction and fetal complications. Physiological changes in renal haemodynamics may assist in predicting a favourable outcome, but have not been previously reported in these circumstances. We present a case of a successful outcome for both mother and babies, and detail the effects of the pregnancy on transplant function and haemodynamics within the transplant kidney. Without beneficial circumstances, twin pregnancy may be a high risk in renal transplant recipients and may lead to a poor outcome for both transplant and fetuses.

摘要

自发性双胎妊娠在肾移植受者中罕见,并且在移植功能障碍和胎儿并发症方面都带来重大风险。肾血流动力学的生理变化可能有助于预测良好结局,但此前在这些情况下尚未有报道。我们报告一例母婴均获成功的病例,并详细阐述妊娠对移植肾功能和血流动力学的影响。在没有有利情况时,双胎妊娠对肾移植受者可能是高风险的,并且可能导致移植肾和胎儿的不良结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/239a/4421557/364a6b88590c/sfp137fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/239a/4421557/612790dc5cec/sfp137fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/239a/4421557/364a6b88590c/sfp137fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/239a/4421557/612790dc5cec/sfp137fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/239a/4421557/364a6b88590c/sfp137fig2.jpg

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J Bras Nefrol. 2021 Jan-Mar;43(1):121-126. doi: 10.1590/2175-8239-JBN-2020-0016.
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Successful management of twin pregnancy in a woman with advanced chronic kidney disease: A case report.晚期慢性肾病女性双胎妊娠的成功管理:一例报告
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A best-practice position statement on pregnancy after kidney transplantation: focusing on the unsolved questions. The Kidney and Pregnancy Study Group of the Italian Society of Nephrology.

本文引用的文献

1
Pregnancy and the kidney.妊娠与肾脏
J Am Soc Nephrol. 2009 Jan;20(1):14-22. doi: 10.1681/ASN.2008050493. Epub 2008 Dec 31.
2
Report from the National Transplantation Pregnancy Registry: outcomes of pregnancy after transplantation.美国国家移植妊娠登记处报告:移植后妊娠的结局
Clin Transpl. 2006:57-70.
3
Pregnancy after kidney transplantation.肾移植后妊娠
关于肾移植后妊娠的最佳实践立场声明:关注未解决的问题。意大利肾脏病学会的肾脏与妊娠研究组。
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Transplantation. 2007 May 27;83(10):1301-7. doi: 10.1097/01.tp.0000263357.44975.d0.
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Reproduction and transplantation: report on the AST Consensus Conference on Reproductive Issues and Transplantation.生殖与移植:美国移植学会生殖问题与移植共识会议报告
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Pregnancy in women with impaired renal function.肾功能受损女性的妊娠情况。
Clin Nephrol. 1997 May;47(5):281-8.
8
Successful twin pregnancy after renal transplant maintained on cyclosporine A immunosuppression.肾移植后在使用环孢素A免疫抑制治疗的情况下成功实现双胎妊娠。
Obstet Gynecol. 1988 Sep;72(3 Pt 2):459-61.
9
Successful pregnancy of twins in a renal transplant patient with Wegener's granulomatosis.一名患有韦格纳肉芽肿的肾移植患者成功孕育双胞胎。
Nephrol Dial Transplant. 1991;6(2):139-40. doi: 10.1093/ndt/6.2.139.