Cheung Chee Kay, Bhandari Sunil
Department of Renal Medicine , Hull and East Yorkshire Hospitals NHS Trust and Hull York Medical School , East Yorkshire, HU3 2JZ , UK.
NDT Plus. 2010 Feb;3(1):48-50. doi: 10.1093/ndtplus/sfp137. Epub 2009 Sep 23.
Spontaneous twin pregnancy is rare in renal transplant recipients, and confers a significant risk, in terms of both transplant dysfunction and fetal complications. Physiological changes in renal haemodynamics may assist in predicting a favourable outcome, but have not been previously reported in these circumstances. We present a case of a successful outcome for both mother and babies, and detail the effects of the pregnancy on transplant function and haemodynamics within the transplant kidney. Without beneficial circumstances, twin pregnancy may be a high risk in renal transplant recipients and may lead to a poor outcome for both transplant and fetuses.
自发性双胎妊娠在肾移植受者中罕见,并且在移植功能障碍和胎儿并发症方面都带来重大风险。肾血流动力学的生理变化可能有助于预测良好结局,但此前在这些情况下尚未有报道。我们报告一例母婴均获成功的病例,并详细阐述妊娠对移植肾功能和血流动力学的影响。在没有有利情况时,双胎妊娠对肾移植受者可能是高风险的,并且可能导致移植肾和胎儿的不良结局。