Bogner Jennifer, French Louis M, Lange Rael T, Corrigan John D
The Ohio State University , Columbus, OH , USA .
Brain Inj. 2015;29(7-8):905-14. doi: 10.3109/02699052.2015.1005136. Epub 2015 May 7.
Explore relationships among traumatic brain injury (TBI), substance misuse and other mental health disorders in US service members and to identify risk factors for substance misuse.
Service members (n = 93 in final sample) injured while deployed to Operation Enduring Freedom or Operation Iraqi Freedom.
Longitudinal survey at 6 and 12 months post-intake. The following measures were used: problem substance use, Alcohol Expectancies Questionnaire-III, MINI International Neuropsychiatric Interview Substance Abuse Modules, Ohio State University TBI Identification Method, Neurobehavioural Symptom Inventory, Rivermead Post-Concussion Symptoms Questionnaire, Buss-Perry Aggression Questionnaire, Post-Traumatic Stress Disorder Checklist-Civilian Version, Beck Depression Inventory-II, Beck Anxiety Inventory.
More severe TBI and post-traumatic stress disorder (PTSD) symptoms at 6 months post-enrolment were associated with decreased odds of substance misuse 12 months after study enrolment. Alcohol expectancies and incurring a TBI at a younger age increased the odds of substance misuse.
While the ability to generalize the current findings to a larger population is limited, the results provide direction for future studies on the prevention and treatment of substance misuse following TBI. The unexpected protective effect of more severe TBI may result from prospective attention to the injury and its consequences. Greater preventive benefit may result from identifying more service members with elevated risk. Lifetime history of TBI and alcohol expectancies may be candidate indicators for greater attention.
探究美国军人创伤性脑损伤(TBI)、药物滥用与其他心理健康障碍之间的关系,并确定药物滥用的风险因素。
在部署到“持久自由行动”或“伊拉克自由行动”期间受伤的军人(最终样本n = 93)。
在入院后6个月和12个月进行纵向调查。使用了以下测量方法:问题物质使用、《酒精预期问卷-III》、《迷你国际神经精神病学访谈物质滥用模块》、俄亥俄州立大学TBI识别方法、神经行为症状量表、里弗米德脑震荡后症状问卷、巴斯-佩里攻击性问卷、《创伤后应激障碍检查表-平民版》、《贝克抑郁量表-II》、《贝克焦虑量表》。
入伍后6个月时更严重的TBI和创伤后应激障碍(PTSD)症状与研究入伍12个月后药物滥用几率降低相关。酒精预期和较年轻时发生TBI会增加药物滥用的几率。
虽然将当前研究结果推广到更多人群的能力有限,但这些结果为未来关于TBI后药物滥用预防和治疗的研究提供了方向。更严重TBI的意外保护作用可能源于对损伤及其后果的前瞻性关注。识别更多高风险军人可能会带来更大的预防益处。TBI的终生病史和酒精预期可能是需要更多关注的候选指标。