Aström C, Jochumsen P L
Department of Clinical Neurophysiology, University Hospital, Copenhagen, Denmark.
Sleep. 1989 Dec;12(6):508-15. doi: 10.1093/sleep/12.6.508.
Seven pituitary dwarfs between 18 and 28 years old with congenital absence of growth hormone, i.e., isolated growth hormone deficiency (IGHD), were examined with polysomnography. Power spectrum analyses of the delta band showed a significant decrease in power in the delta sleep in the IGHD patients compared with the controls. Power spectrum analyses add a new dimension to the description of sleep, as it evaluates, not only frequency of the electroencephalogram (EEG) in time but also the amplitude of the EEG signal. This means that sleep of same quantity can have different powers; for example, 15 min of stage 4 in one person can have another quality than 15 min of stage 4 in another person. An additional observation was that the power in the delta band in the normal young controls showed a correlation to age, with significant decrease within a 10-year period.
对7名年龄在18至28岁之间、先天性缺乏生长激素即孤立性生长激素缺乏症（IGHD）的垂体性侏儒症患者进行了多导睡眠图检查。δ波频段的功率谱分析显示，与对照组相比，IGHD患者的δ睡眠功率显著降低。功率谱分析为睡眠描述增添了新的维度，因为它不仅评估脑电图（EEG）随时间的频率，还评估EEG信号的幅度。这意味着相同时长的睡眠可能具有不同的功率；例如，一个人15分钟的4期睡眠与另一个人15分钟的4期睡眠可能具有不同的质量。另一个观察结果是，正常年轻对照组的δ波频段功率与年龄相关，在10年期间显著下降。
