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Isolated fibromuscular dysplasia of the coronary ostium: a rare cause of sudden death. Case report and review of the literature.

作者信息

Garcia Rafael A, deRoux Stephen J, Axiotis Constantine A

机构信息

Department of Pathology, SUNY Downstate Medical Center/Kings County Hospital Center, Brooklyn, NY 11203, USA.

Department of Pathology, SUNY Downstate Medical Center/Kings County Hospital Center, Brooklyn, NY 11203, USA; City of New York Office of the Chief Medical Examiner, New York, NY 10016, USA.

出版信息

Cardiovasc Pathol. 2015 Sep-Oct;24(5):327-31. doi: 10.1016/j.carpath.2015.04.006. Epub 2015 Apr 20.

DOI:10.1016/j.carpath.2015.04.006
PMID:25953280
Abstract

We present a unique case of sudden death in a 21-year-old man with history of cocaine use and a solitary fibromuscular dysplastic lesion completely occluding the left coronary artery ostium. We document intimal proliferation of myofibroblasts at the opening of the left coronary ostium without other concomitant lesions. This report discusses the gross and histologic features of the lesion, explores in careful detail the possible etiologies, and gives a comprehensive literature review of isolated coronary ostial fibromuscular dysplasia presenting with sudden death.

摘要

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