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2
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HSS J. 2014 Jul;10(2):143-52. doi: 10.1007/s11420-014-9386-8. Epub 2014 Jun 7.
3
Forearm compartment syndrome.前臂骨筋膜室综合征
Eplasty. 2014 Apr 23;14:ic10. eCollection 2014.
4
Extravasation of Noncytotoxic Drugs: A Review of the Literature.非细胞毒性药物外渗:文献综述
Ann Pharmacother. 2014 Jul;48(7):870-886. doi: 10.1177/1060028014527820. Epub 2014 Apr 8.
5
Compartment syndrome due to extravasation of contrast material: a case report.造影剂外渗导致的骨筋膜室综合征:一例报告
Am J Emerg Med. 2014 Sep;32(9):1155.e3-5. doi: 10.1016/j.ajem.2014.02.042. Epub 2014 Mar 5.
6
Tissue necrosis after propofol extravasation.异丙酚外渗后的组织坏死。
Intensive Care Med. 2014 Jan;40(1):129-30. doi: 10.1007/s00134-013-3137-z. Epub 2013 Nov 6.
7
Propofol extravasation and tissue necrosis.丙泊酚外渗与组织坏死。
Indian J Dermatol. 2012 Jan;57(1):78-9. doi: 10.4103/0019-5154.92692.
8
Acute compartment syndrome in the absence of fracture.无骨折情况下的急性骨筋膜室综合征
J Orthop Trauma. 2004 Apr;18(4):220-4. doi: 10.1097/00005131-200404000-00005.
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丙泊酚外渗:骨筋膜室综合征的罕见病因

Propofol extravasation: a rare cause of compartment syndrome.

作者信息

Kalraiya Ashish Jain, Madanipour Suroosh, Colaco Henry, Cobiella Carlos

机构信息

Department of Orthopaedics, West Middlesex University Hospital, London, UK.

UCLH, London, UK.

出版信息

BMJ Case Rep. 2015 May 7;2015:bcr2015209360. doi: 10.1136/bcr-2015-209360.

DOI:10.1136/bcr-2015-209360
PMID:25953583
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4434371/
Abstract

We detail a rare cause of forearm compartment syndrome that occurred in an 18-year-old patient who presented with a Glasgow Coma Scale of 13/15 after a mixed drug overdose and subsequently required intubation. She suffered extravasation of her propofol infusion, which resulted in intrinsic compression within her forearm muscle compartments. Fortunately, the diagnosis of compartment syndrome was made swiftly and the patient was taken to theatre within 3 h where she underwent an emergency forearm fasciotomy. She made an uneventful recovery and at follow-up her wounds had healed well with no associated morbidity or loss of function. The learning points of this study highlight the importance of thoroughly understanding the signs and symptoms of compartment syndrome while maintaining a high index of suspicion. In addition to a thorough history and examination, consideration of the potential underlying causes allows for a swifter diagnosis and a quicker transition to theatre.

摘要

我们详细介绍了一例罕见的前臂骨筋膜室综合征病例,该病例发生在一名18岁患者身上,该患者在混合药物过量后格拉斯哥昏迷评分为13/15,随后需要插管。她的丙泊酚输注发生了外渗,导致前臂肌肉间隙内的内在压迫。幸运的是,骨筋膜室综合征的诊断迅速做出,患者在3小时内被送往手术室,在那里接受了紧急前臂筋膜切开术。她恢复顺利,随访时伤口愈合良好,无相关并发症或功能丧失。本研究的经验教训强调了在保持高度怀疑指数的同时,彻底了解骨筋膜室综合征体征和症状的重要性。除了详细的病史和检查外,考虑潜在的病因有助于更快地做出诊断,并更快地转入手术室。