Edwards D S, Barbur S A R, Bull A M J, Stranks G J
Royal Centre for Defence Medicine, Birmingham, UK,
Eur J Orthop Surg Traumatol. 2015 Aug;25(6):1051-5. doi: 10.1007/s00590-015-1646-x. Epub 2015 May 8.
Heterotopic ossification (HO) is the formation of bone at extra-skeletal sites. Reported rates of HO after hip arthroplasty range from 8 to 90 %; however, it is only severe cases that cause problems clinically, such as joint stiffness. The effects of surgical-related controllable intra-operative risk factors for the formation of HO were investigated. Data examined included gender, age of patient, fat depth, length of operation, incision length, prosthetic fixation method, the use of pulsed lavage and canal brush, and component size and material. All cases were performed by the same surgeon using the posterior approach. A total of 510 cases of hip arthroplasty were included, with an overall rate of HO of 10.2 %. Longer-lasting operations resulted in higher grades of HO (p = 0.047). Incisions >10 cm resulted in more widespread HO formation (p = 0.021). No further correlations were seen between HO formation and fat depth, blood loss, instrumentation, fixation methods or prosthesis material. The mini-incision approach is comparable to the standard approach in the aetiology of HO formation, and whilst the rate of HO may not be controllable, a posterior mini-incision approach can limit its extent.
异位骨化(HO)是指在骨骼外部位形成骨组织。据报道,髋关节置换术后HO的发生率在8%至90%之间;然而,只有严重病例才会在临床上引发问题,如关节僵硬。本研究调查了与手术相关的可控术中危险因素对HO形成的影响。所检查的数据包括性别、患者年龄、脂肪厚度、手术时长、切口长度、假体固定方法、脉冲冲洗和髓腔刷的使用情况,以及假体组件的尺寸和材料。所有病例均由同一位外科医生采用后入路进行手术。共纳入510例髋关节置换病例,HO的总体发生率为10.2%。手术时间越长,HO的分级越高(p = 0.047)。切口长度>10 cm会导致HO形成更为广泛(p = 0.021)。未发现HO形成与脂肪厚度、失血量、器械使用、固定方法或假体材料之间存在进一步的相关性。在HO形成的病因方面,小切口入路与标准入路相当,虽然HO的发生率可能无法控制,但后外侧小切口入路可以限制其范围。