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上颌骨增量部位种植体的生物力学稳定性:一项关于四种不同生物材料和富血小板纤维蛋白的随机临床研究结果及引导骨再生的生物学观点

Biomechanical Stability of Dental Implants in Augmented Maxillary Sites: Results of a Randomized Clinical Study with Four Different Biomaterials and PRF and a Biological View on Guided Bone Regeneration.

作者信息

Angelo Troedhan, Marcel Wainwright, Andreas Kurrek, Izabela Schlichting

机构信息

Institute for Maxillofacial Surgery and Dentistry, General Hospital of Vienna "Hietzing", Wolkersbergenstraße 1, Pavillon 3a, 1130 Vienna, Austria.

Implantology Clinic Kaiserswerth, Kaiserswerther Markt 25, 40489 Dusseldorf, Germany.

出版信息

Biomed Res Int. 2015;2015:850340. doi: 10.1155/2015/850340. Epub 2015 Apr 12.

Abstract

INTRODUCTION

Bone regenerates mainly by periosteal and endosteal humoral and cellular activity, which is given only little concern in surgical techniques and choice of bone grafts for guided bone regeneration. This study investigates on a clinical level the biomechanical stability of augmented sites in maxillary bone when a new class of moldable, self-hardening calcium-phosphate biomaterials (SHB) is used with and without the addition of Platelet Rich Fibrin (aPRF) in the Piezotome-enhanced subperiosteal tunnel-technique (PeSPTT).

MATERIAL AND METHODS

82 patients with horizontal atrophy of anterior maxillary crest were treated with PeSPTT and randomly assigned biphasic (60% HA/40% bTCP) or monophasic (100% bTCP) SHB without or with addition of aPRF. 109 implants were inserted into the augmented sites after 8.3 months and the insertion-torque-value (ITV) measured as clinical expression of the (bio)mechanical stability of the augmented bone and compared to ITVs of a prior study in sinus lifting.

RESULTS

Significant better results of (bio)mechanical stability almost by two-fold, expressed by higher ITVs compared to native bone, were achieved with the used biomaterials and more constant results with the addition of aPRF.

CONCLUSION

The use of SHB alone or combined with aPRF seems to be favourable to achieve a superior (bio)mechanical stable restored alveolar bone.

摘要

引言

骨主要通过骨膜和骨内膜的体液及细胞活动进行再生,然而在引导骨再生的手术技术和骨移植材料选择中,这一点很少受到关注。本研究在临床层面探讨了在压电骨刀辅助骨膜下隧道技术(PeSPTT)中,使用新型可塑形、自固化磷酸钙生物材料(SHB)并添加或不添加富血小板纤维蛋白(aPRF)时,上颌骨植骨部位的生物力学稳定性。

材料与方法

82例上颌前牙嵴水平萎缩患者接受了PeSPTT治疗,并随机分配使用双相(60% HA/40% bTCP)或单相(100% bTCP)SHB,且添加或不添加aPRF。8.3个月后,将109颗种植体植入植骨部位,并测量植入扭矩值(ITV),作为植骨部位(生物)力学稳定性的临床指标,并与之前一项上颌窦提升研究中的ITV进行比较。

结果

与天然骨相比,使用的生物材料实现了(生物)力学稳定性显著提高近两倍,表现为更高的ITV,并且添加aPRF后结果更稳定。

结论

单独使用SHB或与aPRF联合使用似乎有利于实现更高的(生物)力学稳定的牙槽骨修复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c539/4410536/a14e227c947a/BMRI2015-850340.001.jpg

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