• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

大鼠接受手机类型辐射后造血系统的遗传毒性分析。

A genotoxic analysis of the hematopoietic system after mobile phone type radiation exposure in rats.

作者信息

Kumar Gaurav, McIntosh Robert L, Anderson Vitas, McKenzie Ray J, Wood Andrew W

机构信息

a Brain and Psychological Sciences Research Centre, Swinburne University of Technology , Hawthorn, Victoria , Australia.

出版信息

Int J Radiat Biol. 2015 Aug;91(8):664-72. doi: 10.3109/09553002.2015.1047988. Epub 2015 Jun 3.

DOI:10.3109/09553002.2015.1047988
PMID:25955504
Abstract

PURPOSE

In our earlier study we reported that 900 MHz continuous wave (CW) radiofrequency radiation (RFR) exposure (2 W/kg specific absorption rate [SAR]) had no significant effect on the hematopoietic system of rats. In this paper we extend the scope of the previous study by testing for possible effects at: (i) different SAR levels; (ii) both 900 and 1800 MHz, and; (iii) both CW and pulse modulated (PM) RFR.

MATERIALS AND METHODS

Excised long bones from rats were placed in medium and RFR exposed in (i) a Transverse Electromagnetic (TEM) cell or (ii) a waveguide. Finite-difference time-domain (FDTD) numerical analyses were used to estimate forward power needed to produce nominal SAR levels of 2/10 and 2.5/12.4 W/kg in the bone marrow. After exposure, the lymphoblasts were extracted and assayed for proliferation rate, and genotoxicity.

RESULTS

Our data did not indicate any significant change in these end points for any combination of CW/PM exposure at 900/1800 MHz at SAR levels of nominally 2/10 W/kg or 2.5/12.4 W/kg.

CONCLUSIONS

No significant changes were observed in the hematopoietic system of rats after the exposure of CW/PM wave 900 MHz/1800 MHz RF radiations at different SAR values.

摘要

目的

在我们早期的研究中,我们报告称900兆赫连续波(CW)射频辐射(RFR)暴露(比吸收率[SAR]为2瓦/千克)对大鼠的造血系统没有显著影响。在本文中,我们通过测试以下方面的可能影响来扩展先前研究的范围:(i)不同的SAR水平;(ii)900兆赫和1800兆赫两个频率,以及;(iii)连续波(CW)和脉冲调制(PM)RFR。

材料与方法

将大鼠的离体长骨置于培养基中,并在(i)横向电磁(TEM)室或(ii)波导中进行RFR暴露。使用时域有限差分(FDTD)数值分析来估计在骨髓中产生标称SAR水平为2/10和2.5/12.4瓦/千克所需的前向功率。暴露后,提取淋巴母细胞并检测其增殖率和遗传毒性。

结果

我们的数据表明,在标称SAR水平为2/10瓦/千克或2.5/12.4瓦/千克的情况下,900/1800兆赫的CW/PM暴露的任何组合在这些终点上均未显示出任何显著变化。

结论

在不同SAR值下暴露于900兆赫/1800兆赫的CW/PM波射频辐射后,未观察到大鼠造血系统有显著变化。

相似文献

1
A genotoxic analysis of the hematopoietic system after mobile phone type radiation exposure in rats.大鼠接受手机类型辐射后造血系统的遗传毒性分析。
Int J Radiat Biol. 2015 Aug;91(8):664-72. doi: 10.3109/09553002.2015.1047988. Epub 2015 Jun 3.
2
935 MHz cellular phone radiation. An in vitro study of genotoxicity in human lymphocytes.935兆赫手机辐射。人体淋巴细胞遗传毒性的体外研究。
Int J Radiat Biol. 2006 May;82(5):339-46. doi: 10.1080/09553000600739173.
3
Micronuclei in the peripheral blood and bone marrow cells of rats exposed to 2450 MHz radiofrequency radiation.暴露于2450兆赫兹射频辐射的大鼠外周血和骨髓细胞中的微核
Int J Radiat Biol. 2001 Nov;77(11):1109-15. doi: 10.1080/09553000110069100.
4
Measurement of DNA damage after acute exposure to pulsed-wave 2450 MHz microwaves in rat brain cells by two alkaline comet assay methods.采用两种碱性彗星试验方法测定大鼠脑细胞急性暴露于2450 MHz脉冲波微波后的DNA损伤。
Int J Radiat Biol. 2004 Jan;80(1):11-20. doi: 10.1080/09553000310001642911.
5
Evaluation of hematopoietic system effects after in vitro radiofrequency radiation exposure in rats.评估大鼠体外射频辐射暴露后造血系统的影响。
Int J Radiat Biol. 2011 Feb;87(2):231-40. doi: 10.3109/09553002.2010.518212. Epub 2010 Nov 4.
6
Ornithine decarboxylase activity is affected in primary astrocytes but not in secondary cell lines exposed to 872 MHz RF radiation.鸟氨酸脱羧酶活性在原代星形胶质细胞中受到影响,但在暴露于872兆赫射频辐射的传代细胞系中不受影响。
Int J Radiat Biol. 2007 Jun;83(6):367-74. doi: 10.1080/09553000701317341.
7
Sensitivity of spiral ganglion neurons to damage caused by mobile phone electromagnetic radiation will increase in lipopolysaccharide-induced inflammation in vitro model.在脂多糖诱导的体外炎症模型中,螺旋神经节神经元对手机电磁辐射造成损伤的敏感性会增加。
J Neuroinflammation. 2015 May 29;12:105. doi: 10.1186/s12974-015-0300-1.
8
Non-thermal DNA breakage by mobile-phone radiation (1800 MHz) in human fibroblasts and in transformed GFSH-R17 rat granulosa cells in vitro.手机辐射(1800兆赫)对人成纤维细胞和体外转化的GFSH-R17大鼠颗粒细胞的非热DNA断裂作用
Mutat Res. 2005 Jun 6;583(2):178-83. doi: 10.1016/j.mrgentox.2005.03.006.
9
Evaluation of the cytogenotoxic damage in immature and mature rats exposed to 900 MHz radiofrequency electromagnetic fields.评估未成年和成年大鼠暴露于 900MHz 射频电磁场中的细胞遗传毒性损伤。
Int J Radiat Biol. 2013 Nov;89(11):985-92. doi: 10.3109/09553002.2013.809170. Epub 2013 Jun 21.
10
1439 MHz pulsed TDMA fields affect performance of rats in a T-maze task only when body temperature is elevated.1439兆赫脉冲时分多址(TDMA)场仅在体温升高时才会影响大鼠在T型迷宫任务中的表现。
Bioelectromagnetics. 2003 May;24(4):223-30. doi: 10.1002/bem.10099.

引用本文的文献

1
Lessons and Perspectives from a 25-Year Bioelectromagnetics Research Program.一个为期25年的生物电磁学研究项目的经验与展望。
Int J Environ Res Public Health. 2016 Sep 23;13(10):950. doi: 10.3390/ijerph13100950.