一名小儿原位肝移植患者的淋巴瘤与高钙血症
Lymphoma and hypercalcemia in a pediatric orthotopic liver transplant patient.
作者信息
Nakazato P, Esquivel C O, Urbach A H, Makowka L, Scantlebury V, Jaffe R, Starzl T E
机构信息
Transplant Service, San Francisco, CA 94120.
出版信息
Transplantation. 1989 Dec;48(6):1003-6. doi: 10.1097/00007890-198912000-00022.
Abstract
We present a case report of a pediatric orthotopic liver transplant recipient who developed lymphoma with hypercalcemia on cyclosporine and prednisone immunosuppression. This is the first reported posttransplant lymphoproliferative disorder complicated by hypercalcemia, with a finding of an elevated 1,25 dihydroxyl vitamin D state, suggesting that it has a role in the pathophysiology of this B cell lymphoma hypercalcemia. The clinical course and management of this disorder with a 31-month follow-up are described.
摘要
我们报告了一例小儿原位肝移植受者的病例，该受者在接受环孢素和泼尼松免疫抑制治疗时发生了伴有高钙血症的淋巴瘤。这是首例报告的并发高钙血症的移植后淋巴细胞增生性疾病，发现1,25-二羟维生素D水平升高，提示其在这种B细胞淋巴瘤高钙血症的病理生理学中起作用。本文描述了该疾病的临床病程及31个月随访的治疗情况。
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