揭示神经胶质瘤生长之谜。

Shedding light on glioma growth.

机构信息

Department of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.

出版信息

Cell. 2015 May 7;161(4):704-6. doi: 10.1016/j.cell.2015.04.036.

DOI:10.1016/j.cell.2015.04.036

PMID:25957677

Abstract

Cancer is known for opportunistically utilizing resources from its surroundings for its own growth and survival. In this issue of Cell, Venkatesh et al. demonstrate that this also occurs in the brain, identifying neuronal activity-induced secretion of neuroligin-3 as a novel mechanism promoting glioma proliferation.

摘要

癌症以机会主义地利用其周围环境的资源来促进自身生长和存活而闻名。在本期《细胞》杂志中，Venkatesh 等人表明，这种情况也发生在大脑中，他们确定神经元活性诱导的神经黏附素-3 分泌是促进神经胶质瘤增殖的新机制。