Kitai I C, Sanders D M, Manungo J
Department of Paediatrics, University of Zimbabwe Medical School, Harare.
Trop Geogr Med. 1989 Jul;41(3):274-6.
A nine-month-old child received intermittent oral prednisolone over a 6 month period because of persistent wheezing. This therapy had appeared to improve his symptoms. At 15 months of age, a chest X-ray and culture of tracheal aspirate revealed disseminated pulmonary tuberculosis. Response to antituberculous therapy was slow, and withdrawal of steroids produced marked worsening of wheeze and respiratory distress. Corticosteroids are recognised adjuncts in the management of bronchial-lymph node tuberculosis. Responsiveness of wheezing to prednisolone does not imply that its cause is hyperreactive airways disease, and other causes should be sought particularly in developing countries.
一名9个月大的儿童因持续喘息在6个月内间断口服泼尼松龙。这种治疗似乎改善了他的症状。15个月大时，胸部X光检查和气管吸出物培养显示播散性肺结核。抗结核治疗反应缓慢，停用类固醇后喘息和呼吸窘迫明显加重。皮质类固醇是支气管淋巴结结核治疗中公认的辅助药物。喘息对泼尼松龙有反应并不意味着其病因是气道高反应性疾病，在发展中国家尤其应寻找其他病因。
