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冠状动脉血运重建术的治疗结果是否存在社会经济差异——一项基于登记的队列研究

Are there socioeconomic differences in outcomes of coronary revascularizations--a register-based cohort study.

作者信息

Manderbacka Kristiina, Arffman Martti, Lumme Sonja, Keskimäki Ilmo

机构信息

1 Health and Social Systems Research Unit, Department of Health and Social Care Systems, National Institute for Health and Welfare, P. O. Box 30, 00271 Helsinki, Finland

1 Health and Social Systems Research Unit, Department of Health and Social Care Systems, National Institute for Health and Welfare, P. O. Box 30, 00271 Helsinki, Finland.

出版信息

Eur J Public Health. 2015 Dec;25(6):984-9. doi: 10.1093/eurpub/ckv086. Epub 2015 May 9.

Abstract

BACKGROUND

Earlier studies have reported socioeconomic differences in coronary heart disease incidence and mortality and in coronary treatment, but less is known about outcomes of care. We examined trends in income group differences in outcomes of coronary revascularizations among Finnish residents in 1998-2010.

METHODS

First revascularizations for 45-84-year-old Finns were extracted from the Hospital Discharge Register in 1998-2009 and followed until 31 December 2010. Income was individually linked to them and adjusted for family size. We examined the risk of major adverse cardiac events (MACEs), coronary mortality and re-revascularization. We calculated age-standardized rates with direct method and Cox regression models.

RESULTS

Altogether 69 076 men and 27 498 women underwent revascularization during the study period. Among men [women] in the 1998 cohort, 41% [35%] suffered MACE during 29 days after the operation and 30% [28%] in the 2009 cohort. Myocardial infarction mortality within 1 year was 2% among both genders in both cohorts. Among men [women] 9% [14%] underwent revascularization within 1 year after the operation in 1998 and 12% [12%] in 2009. Controlling for age, co-morbidities, year, previous infarction and disease severity, an inverse income gradient was found in MACE incidence within 29 days and in coronary mortality. The excess MACE risk was 1.39 and excess mortality risk over 1.70 among both genders in the lowest income quintile. All income group differences remained stable from 1998 to 2010.

CONCLUSIONS

In health care, more attention should be paid to prevention of adverse outcomes among persons with low socioeconomic position undergoing revascularization.

摘要

背景

早期研究报告了冠心病发病率、死亡率以及冠状动脉治疗方面的社会经济差异,但对于医疗结局了解较少。我们研究了1998 - 2010年芬兰居民冠状动脉血运重建结局的收入群体差异趋势。

方法

从1998 - 2009年医院出院登记册中提取45 - 84岁芬兰人的首次血运重建病例,并随访至2010年12月31日。将收入与个体病例进行关联,并根据家庭规模进行调整。我们研究了主要不良心脏事件(MACE)、冠状动脉死亡率和再次血运重建的风险。我们使用直接法和Cox回归模型计算年龄标准化率。

结果

在研究期间,共有69076名男性和27498名女性接受了血运重建。在1998年队列的男性[女性]中,41%[35%]在术后29天内发生MACE,2009年队列中这一比例为30%[28%]。两个队列中,男女1年内心肌梗死死亡率均为2%。在1998年,男性[女性]中有9%[14%]在术后1年内接受了血运重建,2009年这一比例为12%[12%]。在控制年龄、合并症、年份、既往梗死和疾病严重程度后,发现术后29天内MACE发生率和冠状动脉死亡率存在收入梯度反向关系。最低收入五分位数组中,男女MACE额外风险为1.39,死亡额外风险超过1.70。从1998年到2010年,所有收入群体差异保持稳定。

结论

在医疗保健中,应更加关注社会经济地位较低的接受血运重建者不良结局的预防。

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