Surányi Andrea, Kozinszky Zoltán, Molnár András, Németh Gábor
a Department of Obstetrics and Gynecology , University of Szeged , Szeged , Hungary and.
b Reproductive Medicine, Department of Obstetrics and Gynaecology , Karolinska University Hospital , Stockholm , Sweden.
J Matern Fetal Neonatal Med. 2016;29(8):1229-32. doi: 10.3109/14767058.2015.1040985. Epub 2015 May 11.
Our purpose was to analyze the fetal weight and placental volume (PV) ratio in diabetic pregnancies during mid-pregnancy.
One hundred and forty nine diabetic pregnancies [75 gestational diabetes mellitus (GDM) and 74 diabetes mellitus type I (T1DM) with good glycemic control] and 232 healthy patients were analyzed by three-dimensional sonographic volumetry of the placenta, while fetal weight was estimated by two-dimensional technique.
The gestational age-specific estimated fetal weight (EFW) [EFWGDM: 1840.8 ± 932.82 g; EFWT1DM: 1475.6 ± 914.7 g (mean ± standard deviation) and placental ratio (PR)] was significantly higher (p < 0.05) in pregnancies complicated by GDM and T1DM (PRGDM: 5.5 ± 1.67 g/cm(3), PRT1DM: 4.56 ± 3.2 g/cm(3)) compared to control group (Q) (EFWQ: 532 ± 186.49 g; PRQ: 2.2 ± 0.8 g/cm(3)), whereas PV was significantly higher (p < 0.05) only in GDM (PVGDM: 334.3 ± 111.5 cm(3)) compared to control data (PVQ: 232 ± 78.9 cm(3)). In contrast to GDM, T1DM with good glycemic control did not predispose to any changes in placental sonographic volumetric differences compared to control values.
Fetal weight related to the PV is already elevated in second trimester in pregnancies complicated by gestational diabetes mellitus and type I diabetes mellitus compared to normal pregnancies.
我们的目的是分析妊娠中期糖尿病孕妇的胎儿体重与胎盘体积（PV）之比。
对149例糖尿病孕妇[75例妊娠期糖尿病（GDM）和74例血糖控制良好的I型糖尿病（T1DM）]和232例健康孕妇进行胎盘三维超声容积测量，同时采用二维技术估计胎儿体重。
与对照组（Q）相比，GDM和T1DM合并妊娠的特定孕周估计胎儿体重（EFW）[EFWGDM：1840.8±932.82 g；EFWT1DM：1475.6±914.7 g（均值±标准差）]和胎盘比值（PR）显著更高（p<0.05）（PRGDM：5.5±1.67 g/cm³，PRT1DM：4.56±3.2 g/cm³），而对照组（EFWQ：532±186.49 g；PRQ：2.2±0.8 g/cm³）；与对照数据（PVQ：232±78.9 cm³）相比，仅GDM组的PV显著更高（p<0.05）（PVGDM：334.3±111.5 cm³）。与GDM不同，血糖控制良好的T1DM与对照值相比，胎盘超声容积差异无任何变化。
与正常妊娠相比，妊娠中期合并妊娠期糖尿病和I型糖尿病的孕妇中，与PV相关的胎儿体重已经升高。
