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脑型弓形虫病的类卒中表现:两例HIV感染病例

Stroke-Like Presentation of Cerebral Toxoplasmosis: Two HIV-Infected Cases.

作者信息

Philip-Ephraim Ekanem E, Charidimou Andreas, Williams Effiong, Kajogbola Gbenga

机构信息

Neurology Unit, Department of Internal Medicine, University of Calabar Teaching Hospital, London, UK.

UCL Institute of Neurology and The National Hospital for Neurology and Neurosurgery, London, UK.

出版信息

Cerebrovasc Dis Extra. 2015 Mar 20;5(1):28-30. doi: 10.1159/000375180. eCollection 2015 Jan-Apr.

DOI:10.1159/000375180
PMID:25960735
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4395826/
Abstract

Toxoplasmosis is the most common opportunistic infection of the central nervous system in patients with acquired immunodeficiency syndrome (AIDS). Clinical presentation of cerebral toxoplasmosis in these patients includes headache, focal neurological deficits and seizures. Prompt diagnosis and appropriate therapy results in rapid clinical and radiological improvement as well as good outcome for patients. In this article, we report two cases with stroke-like presentation of cerebral toxoplasmosis in the setting of HIV infection.

摘要

弓形虫病是获得性免疫缺陷综合征(AIDS)患者中枢神经系统最常见的机会性感染。这些患者脑弓形虫病的临床表现包括头痛、局灶性神经功能缺损和癫痫发作。及时诊断和适当治疗可使患者临床和影像学迅速改善,并取得良好预后。在本文中,我们报告了两例在HIV感染情况下出现类似中风表现的脑弓形虫病病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c68/4395826/5e3bec9fde9b/cee-0005-0028-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c68/4395826/5e3bec9fde9b/cee-0005-0028-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c68/4395826/5e3bec9fde9b/cee-0005-0028-g01.jpg

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HIV-Related Cerebral Toxoplasmosis Revisited: Current Concepts and Controversies of an Old Disease.再探与HIV相关的脑弓形虫病:一种古老疾病的当前概念与争议
J Int Assoc Provid AIDS Care. 2019 Jan-Dec;18:2325958219867315. doi: 10.1177/2325958219867315.
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Incidence of stroke in patients with HIV infection: A population-based study in Taiwan.台湾地区基于人群的 HIV 感染患者中风发病率研究。

本文引用的文献

1
Epidemiology of human immunodeficiency virus infection and associated neurologic illness.人类免疫缺陷病毒感染及相关神经系统疾病的流行病学
Semin Neurol. 1999;19(2):105-11. doi: 10.1055/s-2008-1040829.
2
Toxoplasmosis of the central nervous system in the acquired immunodeficiency syndrome.获得性免疫缺陷综合征中的中枢神经系统弓形虫病
N Engl J Med. 1992 Dec 3;327(23):1643-8. doi: 10.1056/NEJM199212033272306.
PLoS One. 2019 May 22;14(5):e0217147. doi: 10.1371/journal.pone.0217147. eCollection 2019.