Patai K, Szarvas Z, Balogh I
2nd Department of Obstetrics and Gynecology, Sommolweis University Medical School, Budapest, Hungary.
Acta Chir Hung. 1989;30(3):199-204.
During progestogen treatment, nickel ions were detected in the human endometrial tissue of patients with endometrial carcinoma by the dimethyloxime cytochemical method. In this paper, the mechanism of action of nickel is dealt with and, because nickel ions have earlier not be detected in human endometrial carcinomatous tissues, the question arises as a result of what kind of cell biological processes, nickel ions appear in the cells of endometrial carcinoma. It is still to be answered whether the progestogen treatment applied can be correlated with the appearance of the trace element in the carcinomatous cell.
在孕激素治疗期间，采用丁二肟细胞化学方法在子宫内膜癌患者的人子宫内膜组织中检测到了镍离子。本文探讨了镍的作用机制，并且由于此前未在人子宫内膜癌组织中检测到镍离子，因此出现了一个问题，即镍离子是由于何种细胞生物学过程而出现在子宫内膜癌细胞中的。应用的孕激素治疗是否与癌细胞中微量元素的出现有关，这一问题仍有待解答。
