Hybels Celia F, Bennett Joan M, Landerman Lawrence R, Liang Jersey, Plassman Brenda L, Wu Bei
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, NC, USA.
Int J Geriatr Psychiatry. 2016 Jan;31(1):83-91. doi: 10.1002/gps.4292. Epub 2015 May 11.
Adverse outcomes associated with chronic depressive symptoms are of clinical importance. The objective was to identify subgroups of older adults based on their trajectories of depressive symptoms over a 10-year period and determine if these subgroups predicted oral health outcomes.
The sample was 944 adults aged 65+ who participated in the oral health module of the the Health and Retirement Survey in 2008. Depressive symptoms were measured with a modified version of the Center for Epidemiologic Studies-Depression (CES-D) scale. Latent class trajectory analysis was used to identify distinct subgroups of elders based on their CES-D scores from 1998-2008. Group membership was used to predict self-rated oral health, overall mouth condition (problems with bleeding gums, gum sensitivity, and food avoidance), and edentulism in 2008.
Three distinct subgroups were identified using zero-inflated Poisson regression models: (i) minimal depressive symptoms over the study period (43%), (ii) low but generally stable level of depressive symptoms (41%), and (iii) moderate symptoms and higher CES-D scores than the other groups over the 10 years (16%). Controlling for demographic and health variables and edentulism status, having a trajectory of moderate symptoms was associated with poorer mouth condition (p < 0.0001) and poorer self-rated oral health (p = 0.0003) compared with those with minimal symptoms. Having low levels of depressive symptoms was not significantly associated with these two outcomes. Group membership was not significantly associated with the probability of edentulism.
Chronic moderate depressive symptoms are associated with poorer oral health in older adults.
与慢性抑郁症状相关的不良后果具有临床重要性。本研究旨在根据老年人在10年期间的抑郁症状轨迹确定亚组,并确定这些亚组是否能预测口腔健康状况。
样本为944名65岁及以上的成年人,他们参与了2008年健康与退休调查中的口腔健康模块。抑郁症状采用流行病学研究中心抑郁量表(CES-D)的修订版进行测量。潜在类别轨迹分析用于根据1998年至2008年的CES-D评分确定老年人的不同亚组。用分组情况来预测2008年的自评口腔健康、总体口腔状况(牙龈出血、牙龈敏感和避免进食方面的问题)以及无牙情况。
使用零膨胀泊松回归模型确定了三个不同的亚组:(i)研究期间抑郁症状轻微(43%),(ii)抑郁症状水平较低但总体稳定(41%),以及(iii)在10年期间症状中度且CES-D评分高于其他组(16%)。在控制人口统计学、健康变量和无牙状况后,与症状轻微的人相比,有中度症状轨迹的人口腔状况较差(p < 0.0001),自评口腔健康较差(p = 0.0003)。抑郁症状水平较低与这两个结果无显著关联。分组情况与无牙概率无显著关联。
慢性中度抑郁症状与老年人较差的口腔健康相关。