巴西多民族人群经颅多普勒检查的颞部声学窗口评估
Evaluation of the Temporal Acoustic Window for Transcranial Doppler in a Multi-Ethnic Population in Brazil.
作者信息
Bazan Rodrigo, Braga Gabriel Pereira, Luvizutto Gustavo José, Hueb João Carlos, Hokama Newton Key, Zanati Bazan Silméia Garcia, de Carvalho Nunes Hélio Rubens, Leite João Pereira, Pontes-Neto Octávio Marques
机构信息
Botucatu Medical School, Department of Neurology and Department of Internal Medicine, University Estadual Paulista Júlio de Mesquita Filho, São Paulo, Brazil.
Botucatu Medical School, Department of Neurology and Department of Internal Medicine, University Estadual Paulista Júlio de Mesquita Filho, São Paulo, Brazil.
出版信息
Ultrasound Med Biol. 2015 Aug;41(8):2131-4. doi: 10.1016/j.ultrasmedbio.2015.04.008. Epub 2015 May 9.
The aim of this study was to relate the presence of a temporal acoustic window (TAW) to the variables sex, age and race. This observational study was conducted in patients under etiologic investigation after stroke, sickle-cell anemia and hospitalization in an intensive therapy neurologic unit. TAW presence was confirmed by bilateral assessment by two neurologists via transcranial Doppler (TCD). Multiple logistic regression was performed to explain the presence of the window as a function of sex, age and race. In 20% of the 262 patients evaluated, a TAW was not present. The incidence of TAW presence was greater in men (odds ratio [OR] = 5.4, 95% confidence interval [CI] = 2.5-11.7, p < 0.01); lower with increased age (OR = 0.9, 95% CI = 0.92-0.97, p < 0.01); and lower among those of African and Asian descent (OR = 0.32, 95% CI = 0.14-0.70, p = 0.005). On the basis of the results, more men than women had TAWs, and the decrease in TAWs was associated with increased age and African or Asian descent.
本研究的目的是探讨颞部声学窗（TAW）的存在与性别、年龄和种族等变量之间的关系。这项观察性研究是在因中风、镰状细胞贫血接受病因调查以及在神经重症监护病房住院的患者中进行的。通过两名神经科医生经颅多普勒（TCD）进行双侧评估来确认TAW的存在。采用多因素logistic回归分析来解释声学窗的存在与性别、年龄和种族之间的函数关系。在评估的262例患者中，20%不存在TAW。男性中TAW存在的发生率更高（优势比[OR]=5.4，95%置信区间[CI]=2.5-11.7，p<0.01）；随着年龄增长发生率降低（OR=0.9，95%CI=0.92-0.97，p<0.01）；在非洲裔和亚裔人群中发生率较低（OR=0.32，95%CI=0.14-0.70，p=0.005）。根据研究结果，男性中拥有TAW的人数多于女性，TAW的减少与年龄增长以及非洲裔或亚裔血统有关。
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