Zia Khalid Mahmood, Zia Fatima, Zuber Mohammad, Rehman Saima, Ahmad Mirza Nadeem
Institute of Chemistry, Government College University, Faisalabad 38030, Pakistan.
Institute of Chemistry, Government College University, Faisalabad 38030, Pakistan.
Int J Biol Macromol. 2015 Aug;79:377-87. doi: 10.1016/j.ijbiomac.2015.04.076. Epub 2015 May 9.
The trend of using biopolymers in combination with synthetic polymers was increasing rapidly from last two or three decades. Polysaccharide based biopolymers especially starch, cellulose, chitin, chitosan, alginate, etc. found extensive applications for different industrial uses, as they are biocompatible, biodegradable, bio-renewable resources and chiefly environment friendly. Segment block copolymer character of polyurethanes that endows them a broad range of versatility in terms of tailoring their properties was employed in conjunction with various natural polymers resulted in modified biomaterials. Alginate is biodegradable, biocompatible, bioactive, less toxic and low cost anionic polysaccharide, as a part of structural component of bacteria and brown algae (sea weed) is quite abundant in nature. It is used in combination with polyurethanes to form elastomers, nano-composites, hydrogels, etc. that especially revolutionized the food and biomedical industries. The review summarized the development in alginate based polyurethanes with their potential applications.
在过去的二三十年里，将生物聚合物与合成聚合物结合使用的趋势迅速增长。基于多糖的生物聚合物，特别是淀粉、纤维素、几丁质、壳聚糖、藻酸盐等，因其具有生物相容性、可生物降解性、生物可再生性且主要对环境友好，在不同工业用途中得到了广泛应用。聚氨酯的嵌段共聚物特性使其在定制性能方面具有广泛的通用性，将其与各种天然聚合物结合使用可得到改性生物材料。藻酸盐是一种可生物降解、生物相容、具有生物活性、低毒且低成本的阴离子多糖，作为细菌和褐藻（海藻）结构成分的一部分，在自然界中相当丰富。它与聚氨酯结合使用可形成弹性体、纳米复合材料、水凝胶等，尤其给食品和生物医学行业带来了变革。本综述总结了基于藻酸盐的聚氨酯的发展及其潜在应用。
