Smith C Daniel
Piedmont Clinic, 2795 Peachtree Road, Unit 1808, Atlanta, GA 30305, USA.
Surg Clin North Am. 2015 Jun;95(3):669-81. doi: 10.1016/j.suc.2015.02.017. Epub 2015 Apr 15.
Esophageal disease and dysfunction of the lower esophageal sphincter (LES) manifesting as gastroesophageal reflux disease (GERD) particularly, is the most common of all gastrointestinal conditions impacting patients on a day-to-day basis. LES dysfunction can lead to anatomic changes to the distal esophagus, with GERD-mediated changes being benign stricture or progression of GERD to Barrett's esophagus and even esophageal cancer, and LES hypertension impairing esophageal emptying with subsequent development of pulsion esophageal diverticulum. This article details the causes, clinical presentation, workup, and treatment of esophageal stricture and epiphrenic esophageal diverticulum. Other types of esophageal diverticula (Zenker's and midesophageal) are also covered.
食管疾病以及表现为胃食管反流病(GERD)的下食管括约肌(LES)功能障碍,尤其是在日常影响患者的所有胃肠道疾病中最为常见。LES功能障碍可导致食管远端的解剖学改变,GERD介导的改变包括良性狭窄、GERD进展为巴雷特食管甚至食管癌,而LES高压会损害食管排空,随后发展为动力性食管憩室。本文详细介绍了食管狭窄和膈上食管憩室的病因、临床表现、检查及治疗。其他类型的食管憩室(Zenker憩室和食管中段憩室)也在讨论范围内。