Dean David S, Parsegian V Adrian, Podgornika Rudolf
Université de Bordeaux and CNRS, Laboratoire Ondes et Matière d'Aquitaine (LOMA), UMR 5798, F-33400 Talence, France.
J Phys Condens Matter. 2015 Jun 3;27(21):214004. doi: 10.1088/0953-8984/27/21/214004. Epub 2015 May 12.
We consider how membrane fluctuations can modify the miscibility of lipid mixtures, that is to say how the phase diagram of a boundary-constrained membrane is modified when the membrane is allowed to fluctuate freely in the case of zero surface tension. In order for fluctuations to have an effect, the different lipid types must have differing Gaussian rigidities. We show, somewhat paradoxically, that fluctuation-induced interactions can be treated approximately in a mean-field type theory. Our calculations predict that, depending on the difference in bending and Gaussian rigidity of the lipids, membrane fluctuations can either favor or disfavor mixing.
我们研究了膜波动如何改变脂质混合物的混溶性，也就是说，在零表面张力的情况下，当允许边界受限的膜自由波动时，其相图会如何变化。为了使波动产生影响，不同类型的脂质必须具有不同的高斯刚性。我们有点自相矛盾地表明，波动诱导的相互作用可以在平均场类型理论中进行近似处理。我们的计算预测，根据脂质弯曲刚性和高斯刚性的差异，膜波动可能有利于或不利于混合。
